ID   MENE_HAEIN              Reviewed;         452 AA.
AC   P44565;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=2-succinylbenzoate--CoA ligase {ECO:0000255|HAMAP-Rule:MF_00731};
DE            EC=6.2.1.26 {ECO:0000255|HAMAP-Rule:MF_00731};
DE   AltName: Full=o-succinylbenzoyl-CoA synthetase {ECO:0000255|HAMAP-Rule:MF_00731};
DE            Short=OSB-CoA synthetase {ECO:0000255|HAMAP-Rule:MF_00731};
GN   Name=menE {ECO:0000255|HAMAP-Rule:MF_00731}; OrderedLocusNames=HI_0194;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA
CC       (OSB-CoA). {ECO:0000255|HAMAP-Rule:MF_00731}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP +
CC         diphosphate; Xref=Rhea:RHEA:17009, ChEBI:CHEBI:18325,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57364, ChEBI:CHEBI:456215; EC=6.2.1.26;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00731};
CC   -!- PATHWAY: Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate
CC       biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 5/7.
CC       {ECO:0000255|HAMAP-Rule:MF_00731}.
CC   -!- PATHWAY: Quinol/quinone metabolism; menaquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00731}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       MenE subfamily. {ECO:0000255|HAMAP-Rule:MF_00731}.
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DR   EMBL; L42023; AAC21863.1; -; Genomic_DNA.
DR   PIR; F64053; F64053.
DR   RefSeq; NP_438363.1; NC_000907.1.
DR   RefSeq; WP_005694098.1; NC_000907.1.
DR   AlphaFoldDB; P44565; -.
DR   SMR; P44565; -.
DR   STRING; 71421.HI_0194; -.
DR   EnsemblBacteria; AAC21863; AAC21863; HI_0194.
DR   KEGG; hin:HI_0194; -.
DR   PATRIC; fig|71421.8.peg.199; -.
DR   eggNOG; COG0318; Bacteria.
DR   HOGENOM; CLU_000022_59_0_6; -.
DR   OMA; PIAYYPL; -.
DR   PhylomeDB; P44565; -.
DR   BioCyc; HINF71421:G1GJ1-205-MON; -.
DR   UniPathway; UPA00079; -.
DR   UniPathway; UPA01057; UER00166.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016405; F:CoA-ligase activity; IBA:GO_Central.
DR   GO; GO:0008756; F:o-succinylbenzoate-CoA ligase activity; IBA:GO_Central.
DR   GO; GO:0009234; P:menaquinone biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; -; 1.
DR   HAMAP; MF_00731; MenE; 1.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR010192; MenE.
DR   Pfam; PF00501; AMP-binding; 1.
DR   TIGRFAMs; TIGR01923; menE; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Ligase; Menaquinone biosynthesis; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..452
FT                   /note="2-succinylbenzoate--CoA ligase"
FT                   /id="PRO_0000193177"
SQ   SEQUENCE   452 AA;  51394 MW;  3EFA6456AC6F7CBF CRC64;
     MYPWQDFAIQ PDFSDKIALR TTQGDMLTWI ELTTKINQTV AFLQKKGVNA ESAVAFVGKN
     SEKILFLYLA TIQLGAKVLG INPAFPQEKI AKLCEFYQID FCFYDKDLLN LQEIDVFTQK
     ADFFRPATMT LTSGSTGLPK AVVHNVQAHL DNAKGVCNLM KFDCNQSWLL SLPLYHVSGQ
     GIVWRWLYCG AQLHFPEDDF YASLLKTTHV SLVPTQLQRL LDYLQENPSI SFATRHILLG
     GAHIPTELTQ NMLKYGIETY SGYGMTEMAS TVFAKKSDRK QGVGQPLLGR EYCLVNDEIW
     LKGAGLAMGY WKDRQIVPLT NNQGWIQTKD KGIWQEGELV IIGRLDNMFI SGGENIQPEE
     IEQVIIQHSS VNQVFVLPQK NKEFGQRPVA LVDFNEPFSK SAVENLMFFL QDKLARFKQP
     IAYYPLPLML EKGIKISRKQ LADWLAKRDE IN