ID   MENG_NOSP7              Reviewed;         230 AA.
AC   B2IUM7;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=2-phytyl-1,4-naphtoquinone methyltransferase {ECO:0000255|HAMAP-Rule:MF_01982};
DE            EC=2.1.1.329 {ECO:0000255|HAMAP-Rule:MF_01982};
DE   AltName: Full=Demethylphylloquinone methyltransferase {ECO:0000255|HAMAP-Rule:MF_01982};
GN   Name=menG {ECO:0000255|HAMAP-Rule:MF_01982}; OrderedLocusNames=Npun_R4434;
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Methyltransferase required for the conversion of 2-phytyl-
CC       1,4-beta-naphthoquinol to phylloquinol. {ECO:0000255|HAMAP-
CC       Rule:MF_01982}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=demethylphylloquinol + S-adenosyl-L-methionine = H(+) +
CC         phylloquinol + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:40551,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:28433, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:87844; EC=2.1.1.329;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01982};
CC   -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01982}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. MenG/UbiE family. {ECO:0000255|HAMAP-Rule:MF_01982}.
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DR   EMBL; CP001037; ACC82802.1; -; Genomic_DNA.
DR   RefSeq; WP_012410763.1; NC_010628.1.
DR   AlphaFoldDB; B2IUM7; -.
DR   SMR; B2IUM7; -.
DR   STRING; 63737.Npun_R4434; -.
DR   EnsemblBacteria; ACC82802; ACC82802; Npun_R4434.
DR   KEGG; npu:Npun_R4434; -.
DR   eggNOG; COG2226; Bacteria.
DR   HOGENOM; CLU_037990_0_0_3; -.
DR   OMA; WQKSALN; -.
DR   OrthoDB; 1431378at2; -.
DR   PhylomeDB; B2IUM7; -.
DR   UniPathway; UPA00995; -.
DR   Proteomes; UP000001191; Chromosome.
DR   GO; GO:0052624; F:2-phytyl-1,4-naphthoquinone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.150; -; 1.
DR   HAMAP; MF_01982; MenG_phylloquinone_subfam; 1.
DR   HAMAP; MF_01813; MenG_UbiE_methyltr; 1.
DR   InterPro; IPR032904; MenG.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR004033; UbiE/COQ5_MeTrFase.
DR   InterPro; IPR023576; UbiE/COQ5_MeTrFase_CS.
DR   Pfam; PF01209; Ubie_methyltran; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR01934; MenG_MenH_UbiE; 1.
DR   PROSITE; PS51608; SAM_MT_UBIE; 1.
DR   PROSITE; PS01183; UBIE_1; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..230
FT                   /note="2-phytyl-1,4-naphtoquinone methyltransferase"
FT                   /id="PRO_1000187782"
SQ   SEQUENCE   230 AA;  25739 MW;  FD83F04B7379CC88 CRC64;
     MTNEVQSIFN RIAPVYDQLN DWLSLGQHRI WKEMAVKWSA AKSGNTALDL CCGSGDLALR
     LARRVGATGY VYGVDFSCNL LETAKERSQK QYPQPAIAWV EADVLNLPFD DNQFDAATMG
     YGLRNVKDIP RSLQELHRVL KPGAKAAILD FHRPSNPQLR AFQQLYLNSF VVPVANYLGL
     KEEYAYISPS LDRFPIGKEQ IELARQVGFA VATHYPIANG MMGVLVVSKF