ID   MENG_SYNP6              Reviewed;         233 AA.
AC   Q5N4X9;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=2-phytyl-1,4-naphtoquinone methyltransferase {ECO:0000255|HAMAP-Rule:MF_01982};
DE            EC=2.1.1.329 {ECO:0000255|HAMAP-Rule:MF_01982};
DE   AltName: Full=Demethylphylloquinone methyltransferase {ECO:0000255|HAMAP-Rule:MF_01982};
GN   Name=menG {ECO:0000255|HAMAP-Rule:MF_01982}; OrderedLocusNames=syc0450_d;
OS   Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS   nidulans).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=269084;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX   PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA   Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA   Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT   "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT   Synechococcus elongatus PCC 6301 chromosome: gene content and
RT   organization.";
RL   Photosyn. Res. 93:55-67(2007).
CC   -!- FUNCTION: Methyltransferase required for the conversion of 2-phytyl-
CC       1,4-beta-naphthoquinol to phylloquinol. {ECO:0000255|HAMAP-
CC       Rule:MF_01982}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=demethylphylloquinol + S-adenosyl-L-methionine = H(+) +
CC         phylloquinol + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:40551,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:28433, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:87844; EC=2.1.1.329;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01982};
CC   -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01982}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. MenG/UbiE family. {ECO:0000255|HAMAP-Rule:MF_01982}.
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DR   EMBL; AP008231; BAD78640.1; -; Genomic_DNA.
DR   RefSeq; WP_011242762.1; NC_006576.1.
DR   AlphaFoldDB; Q5N4X9; -.
DR   SMR; Q5N4X9; -.
DR   STRING; 269084.syc0450_d; -.
DR   EnsemblBacteria; BAD78640; BAD78640; syc0450_d.
DR   KEGG; syc:syc0450_d; -.
DR   eggNOG; COG2226; Bacteria.
DR   OMA; WQKSALN; -.
DR   UniPathway; UPA00995; -.
DR   Proteomes; UP000001175; Chromosome.
DR   GO; GO:0052624; F:2-phytyl-1,4-naphthoquinone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.150; -; 1.
DR   HAMAP; MF_01982; MenG_phylloquinone_subfam; 1.
DR   HAMAP; MF_01813; MenG_UbiE_methyltr; 1.
DR   InterPro; IPR032904; MenG.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR004033; UbiE/COQ5_MeTrFase.
DR   InterPro; IPR023576; UbiE/COQ5_MeTrFase_CS.
DR   Pfam; PF01209; Ubie_methyltran; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR01934; MenG_MenH_UbiE; 1.
DR   PROSITE; PS51608; SAM_MT_UBIE; 1.
DR   PROSITE; PS01183; UBIE_1; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..233
FT                   /note="2-phytyl-1,4-naphtoquinone methyltransferase"
FT                   /id="PRO_0000193341"
SQ   SEQUENCE   233 AA;  25441 MW;  ADD1F2E1E93702E2 CRC64;
     MSVLAPDAVE GLFDQIAPIY DNLNDQLSFG LHRLWKRMAV KWSAAKPGDR VLDLCCGSGD
     LAFLLAKVVG SKGQVIGFDR SQALLSVAGD RARQLASALV IDWQRGDALD LPFPDDHFDA
     ATLGYGLRNV PDIPTVLRQL QRVLKPGARA AILDMHRPYS PLLRQFQQVY LDRWVVPAAA
     AQNCAAEYEY IDASLEAFPQ GQQQVALAIA AGFQRAKHYE LAAGLMGVLV VEA