ID   MENT_RAT                Reviewed;         344 AA.
AC   Q5XI62;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Protein MENT;
DE   AltName: Full=Methylated in normal thymocytes protein;
DE   Flags: Precursor;
GN   Name=Ment;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Involved in control of cellular proliferation. Onconcogenic
CC       modifier contributing to the tumor suppressor function of DNMT3B (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- PTM: Phosphorylation sites are present in the extracellular medium.
CC       {ECO:0000250}.
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DR   EMBL; BC083828; AAH83828.1; -; mRNA.
DR   RefSeq; NP_001007639.1; NM_001007638.1.
DR   AlphaFoldDB; Q5XI62; -.
DR   STRING; 10116.ENSRNOP00000059268; -.
DR   iPTMnet; Q5XI62; -.
DR   PhosphoSitePlus; Q5XI62; -.
DR   PaxDb; Q5XI62; -.
DR   GeneID; 295265; -.
DR   KEGG; rno:295265; -.
DR   UCSC; RGD:1359334; rat.
DR   CTD; 295265; -.
DR   RGD; 1359334; RGD1359334.
DR   VEuPathDB; HostDB:ENSRNOG00000021656; -.
DR   eggNOG; ENOG502SZ3R; Eukaryota.
DR   HOGENOM; CLU_066649_0_0_1; -.
DR   InParanoid; Q5XI62; -.
DR   OMA; WHCHCRS; -.
DR   OrthoDB; 1015642at2759; -.
DR   PRO; PR:Q5XI62; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   Bgee; ENSRNOG00000021656; Expressed in testis and 3 other tissues.
DR   Genevisible; Q5XI62; RN.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042127; P:regulation of cell population proliferation; ISO:RGD.
DR   InterPro; IPR029292; MENT.
DR   PANTHER; PTHR16240; PTHR16240; 1.
DR   Pfam; PF15322; PMSI1; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..344
FT                   /note="Protein MENT"
FT                   /id="PRO_0000304971"
FT   REGION          162..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..188
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   344 AA;  37640 MW;  8A0A161414161664 CRC64;
     MVPAACMLLW ALLLSLESRA AGAEDQKTNP TATTVRMQRV SFHFGGPARS LRSTNPTART
     SISRKLRVTL EDENDALATA DRLAVPAAAE LLSTVTGYSR SSLSNSGDWE EDGSLEEGVV
     DTRKTTNNPI TIFSTTNTVG SSSTTGRFVA NSQEREIRLT TDMRSPSSKT TVDLSSETTL
     QQWSTPGSTP SPWPKPSLTA MPSPEDLRVV LMPWGPWHCH CKSGTMSRSR AGKLHGLSGR
     LRVGALNELR TEHRPCTYQL CTCNRQLEEC PLDSSLCTDH SCSTHVASTI SPIPVHLRRR
     PILPPTSPSP SPALAFWKRV RIGLEDIWNS LSSVFTETQP IERT