ARID2_ARATH
ID ARID2_ARATH Reviewed; 573 AA.
AC Q9LDD4; Q1PEA0;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=AT-rich interactive domain-containing protein 2;
DE Short=ARID domain-containing protein 2;
DE AltName: Full=ARID and ELM2 domain-containing protein 2;
GN Name=ARID2; OrderedLocusNames=At4g11400; ORFNames=F25E4.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
CC -!- INTERACTION:
CC Q9LDD4; Q0WNR6: ARID5; NbExp=3; IntAct=EBI-15200250, EBI-15194457;
CC Q9LDD4; C0SUW7: ARID6; NbExp=3; IntAct=EBI-15200250, EBI-15192335;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355,
CC ECO:0000255|PROSITE-ProRule:PRU00512}.
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DR EMBL; AL050399; CAB82145.1; -; Genomic_DNA.
DR EMBL; AL161531; CAB81241.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE83008.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM68067.1; -; Genomic_DNA.
DR EMBL; DQ446818; ABE66055.1; -; mRNA.
DR PIR; T10560; T10560.
DR RefSeq; NP_001319902.1; NM_001340708.1.
DR RefSeq; NP_192879.1; NM_117211.2.
DR AlphaFoldDB; Q9LDD4; -.
DR SMR; Q9LDD4; -.
DR BioGRID; 12043; 5.
DR IntAct; Q9LDD4; 3.
DR STRING; 3702.AT4G11400.1; -.
DR PaxDb; Q9LDD4; -.
DR PRIDE; Q9LDD4; -.
DR ProteomicsDB; 240973; -.
DR EnsemblPlants; AT4G11400.1; AT4G11400.1; AT4G11400.
DR EnsemblPlants; AT4G11400.2; AT4G11400.2; AT4G11400.
DR GeneID; 826744; -.
DR Gramene; AT4G11400.1; AT4G11400.1; AT4G11400.
DR Gramene; AT4G11400.2; AT4G11400.2; AT4G11400.
DR KEGG; ath:AT4G11400; -.
DR Araport; AT4G11400; -.
DR TAIR; locus:2123061; AT4G11400.
DR eggNOG; ENOG502QVAG; Eukaryota.
DR HOGENOM; CLU_032356_2_0_1; -.
DR InParanoid; Q9LDD4; -.
DR OMA; HIAEARM; -.
DR OrthoDB; 271170at2759; -.
DR PhylomeDB; Q9LDD4; -.
DR PRO; PR:Q9LDD4; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9LDD4; baseline and differential.
DR Genevisible; Q9LDD4; AT.
DR GO; GO:0000118; C:histone deacetylase complex; IDA:TAIR.
DR GO; GO:0005773; C:vacuole; HDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 1.10.150.60; -; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF01388; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SMART; SM01189; ELM2; 1.
DR SUPFAM; SSF46774; SSF46774; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51156; ELM2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..573
FT /note="AT-rich interactive domain-containing protein 2"
FT /id="PRO_0000413210"
FT DOMAIN 24..114
FT /note="ARID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00355"
FT DOMAIN 372..463
FT /note="ELM2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00512"
FT CONFLICT 294
FT /note="P -> L (in Ref. 3; ABE66055)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 573 AA; 65666 MW; C048AAA7181599A5 CRC64;
MGSFNDTSCS YVDVEIKYVD ECEERLRRLF DQALLVFLEE EGSIKPLPAV IGDGKNVDLF
KLFVLVRERE GFDTVSRKRL WEVVAEKLGF DCSLVPSLIL IYLKYLNRME KWAVEESRIV
NWDNKDSEKK GCYSGMLHEL GNGFKSLLDN GKCQKRNRAV AFGCNHMEES CSEFDRSRKR
FRESDDDDKG VGLSSVVIRE ETVVCAVEEG LSDFSLEKRD DLPGMLKWLA LVATSPHDPA
IGVIPHSSKW KQYNGNKCWL QVARAKNSLL VQRDNAELRY RYHPFRGHQN IHHPSMYEDD
RKSIGRLRYS IRPPNLSKHC SSSCCNGSSL VSLSKSRSTK CRKLTIIASE RAGLTAGTSR
ARKRNKAEIP RRCIKVGHQH QAQVDEWTES GVDSDSKWLG TRIWPPENSE ALDQTLGNDL
VGKGRPDSCS CELSGFVECT RLHIAEKRME LKRELGDDFF HWRFNQMGEE VCLRWTEEEE
KRFKDMIIAD PQSFWTNAAK NFPKKKREEL VSYYFNVFLI NRRRYQNRVT PKSIDSDDEG
AFGSVGGSFG RDAVTSSGSD VMICAQNRQC EDY
