ARID3_ARATH
ID ARID3_ARATH Reviewed; 786 AA.
AC Q940Y3; Q67YT6;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=AT-rich interactive domain-containing protein 3;
DE Short=ARID domain-containing protein 3;
GN Name=ARID3; OrderedLocusNames=At2g17410; ORFNames=F5J6.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- INTERACTION:
CC Q940Y3; C0SUW7: ARID6; NbExp=4; IntAct=EBI-15193099, EBI-15192335;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q940Y3-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC {ECO:0000255|PROSITE-ProRule:PRU00285}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002685; AEC06621.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM63318.1; -; Genomic_DNA.
DR EMBL; AY052359; AAK96550.1; -; mRNA.
DR EMBL; BT002633; AAO11549.1; -; mRNA.
DR EMBL; AK176382; BAD44145.1; -; mRNA.
DR EMBL; AK230281; BAF02083.1; -; mRNA.
DR PIR; G84551; G84551.
DR RefSeq; NP_001325412.1; NM_001335547.1. [Q940Y3-1]
DR RefSeq; NP_179333.2; NM_127296.3. [Q940Y3-1]
DR AlphaFoldDB; Q940Y3; -.
DR SMR; Q940Y3; -.
DR BioGRID; 1604; 8.
DR IntAct; Q940Y3; 5.
DR STRING; 3702.AT2G17410.1; -.
DR iPTMnet; Q940Y3; -.
DR PaxDb; Q940Y3; -.
DR PRIDE; Q940Y3; -.
DR ProteomicsDB; 246986; -. [Q940Y3-1]
DR EnsemblPlants; AT2G17410.1; AT2G17410.1; AT2G17410. [Q940Y3-1]
DR EnsemblPlants; AT2G17410.3; AT2G17410.3; AT2G17410. [Q940Y3-1]
DR GeneID; 816247; -.
DR Gramene; AT2G17410.1; AT2G17410.1; AT2G17410. [Q940Y3-1]
DR Gramene; AT2G17410.3; AT2G17410.3; AT2G17410. [Q940Y3-1]
DR KEGG; ath:AT2G17410; -.
DR Araport; AT2G17410; -.
DR TAIR; locus:2827523; AT2G17410.
DR eggNOG; ENOG502RZDH; Eukaryota.
DR HOGENOM; CLU_359179_0_0_1; -.
DR InParanoid; Q940Y3; -.
DR OrthoDB; 190266at2759; -.
DR PhylomeDB; Q940Y3; -.
DR PRO; PR:Q940Y3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q940Y3; baseline and differential.
DR Genevisible; Q940Y3; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0032991; C:protein-containing complex; IPI:TAIR.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 1.10.150.60; -; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR InterPro; IPR045147; ARI3A/B/C.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR15348; PTHR15348; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF00011; HSP20; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; SSF46774; 1.
DR SUPFAM; SSF49764; SSF49764; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS01031; SHSP; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..786
FT /note="AT-rich interactive domain-containing protein 3"
FT /id="PRO_0000413211"
FT DOMAIN 494..585
FT /note="ARID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00355"
FT DOMAIN 686..786
FT /note="sHSP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT REGION 1..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 662
FT /note="L -> S (in Ref. 4; BAD44145)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 786 AA; 86570 MW; 48C4123008B83D3A CRC64;
MENLTEIEST MESLTEMESE RVEQGTDKEI GSGEKRQDDV KETENENSGE RVGEEAPVRE
HEDSPCLIVI EEGTSLASLE EVTNADDLPK IDDEKNSQFE TSPHPSPSPS VALDTEEGLI
NPTAEDTVEE NIVSSEVSSD ILKDDGDAVE VDRDTAEVQE ETANIPESKL SEDTGSPHHH
ADILMVQEKA AEEHDMIASG DHEEFPVNPD NKHSEENQSP HHHANNVMEQ DQAAEEREII
SPGEHKEIPA NPDTKVVEEN NDRIDEGEAN NLNLAGDGSG AVDHDYLTKT ELDKVLEVPG
SETISKLEDR PSEHLSETSM NVEKELEMPA VEILPDNDKN SDVLAVGVSG DSDNVVSVLP
ASQTSSDRDE GMITVDAEPT EDMKLDVPDS KLVTDTTVDS TNNKDAHVEA NTERQDNSSA
LVLNDANNES APVKRVPGPY VASSNIKSEA RGSGDLNNGV HKIVRTPPVF DGTMRAKRSF
LLDDASDGNE SGTEEDQSAF MKELDSFFRE RNMDFKPPKF YGEGLNCLKL WRAVTRLGGY
DKVTGSKLWR QVGESFRPPK TCTTVSWTFR GFYEKALLEY ERHKVSEGEL QIPLPLELEP
MNIDNQASGS GRARRDAASR AMQGWHSQRL NGNGEVSDPA IKDKNLVLHQ KREKQIGTTP
GLLKRKRAAE HGAKNAIHVS KSMLDVTVVD VGPPADWVKI NVQRTQDCFE VYALVPGLVR
EEVRVQSDPA GRLVISGEPE NPMNPWGATP FKKVVSLPTR IDPHHTSAVV TLNGQLFVRV
PLEQLE
