ID   MER1_EUPOC              Reviewed;         150 AA.
AC   O15823;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Mating pheromone 1;
DE   Flags: Precursor;
OS   Euplotoides octocarinatus (Freshwater ciliate) (Euplotes octocarinatus).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Hypotrichia; Euplotida; Euplotidae; Euplotes.
OX   NCBI_TaxID=2716877;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CC-4;
RA   Bruenen-Nieweler C., Weiligmann J.C., Hansen B., Kuhlmann H.W.,
RA   Moellenbeck M., Heckmann K.;
RT   "The pheromones and pheromone genes of new stocks of the Euplotes
RT   octocarinatus species complex.";
RL   Eur. J. Protist. 34:124-132(1998).
CC   -!- FUNCTION: Mating ciliate pheromones (or gamones) are diffusible
CC       extracellular communication signals that distinguish different
CC       intraspecific classes of cells commonly referred to as 'mating types'.
CC       They prepare the latter for conjugation by changing their cell surface
CC       properties.
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   EMBL; Y15316; CAA75578.1; -; Genomic_DNA.
DR   AlphaFoldDB; O15823; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005186; F:pheromone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR008612; Mating_pheromone_EUPOC.
DR   Pfam; PF05842; Euplotes_phero; 1.
PE   3: Inferred from homology;
KW   Pheromone; Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   PROPEP          17..52
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000008674"
FT   PEPTIDE         53..150
FT                   /note="Mating pheromone 1"
FT                   /id="PRO_0000008675"
SQ   SEQUENCE   150 AA;  16690 MW;  4744CBC0D5B22575 CRC64;
     MKAIFIILAI LMVTQAFKMT SKVNTKLQSQ IQSKFQSKNK LASTFQTSSK LKGECDTIIP
     DFTGCNANDA CPLSFTCSAT GNDEQLCNAA GQNVIDMIFA HWSTCWNTYG NCIEFARQTY
     AIYNAPELCG CDYVDEETWI NTLESVCPYV