ID   MER20_EUPRA             Reviewed;          37 AA.
AC   P26888;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Mating pheromone Er-20;
DE   AltName: Full=Euplomone R20;
DE   Flags: Fragment;
GN   Name=MAT20;
OS   Euplotes raikovi.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Hypotrichia; Euplotida; Euplotidae; Euplotes.
OX   NCBI_TaxID=5938;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=GA-4;
RX   PubMed=1549567; DOI=10.1073/pnas.89.6.2071;
RA   Raffioni S., Miceli C., Vallesi A., Chowdhury S.K., Chait B.T.,
RA   Luporini P., Bradshaw R.A.;
RT   "Primary structure of Euplotes raikovi pheromones: comparison of five
RT   sequences of pheromones from cells with variable mating interactions.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:2071-2075(1992).
CC   -!- FUNCTION: Mating ciliate pheromones (or gamones) are diffusible
CC       extracellular communication signals that distinguish different
CC       intraspecific classes of cells commonly referred to as 'mating types'.
CC       They prepare the latter for conjugation by changing their cell surface
CC       properties.
CC   -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   PIR; C41933; C41933.
DR   AlphaFoldDB; P26888; -.
DR   SMR; P26888; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005186; F:pheromone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR009064; Pheromone_protoz.
DR   InterPro; IPR036245; Pheromone_protoz_sf.
DR   Pfam; PF06360; E_raikovi_mat; 1.
DR   SUPFAM; SSF47014; SSF47014; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Pheromone; Secreted.
FT   CHAIN           1..>37
FT                   /note="Mating pheromone Er-20"
FT                   /id="PRO_0000186197"
FT   DISULFID        3..18
FT                   /evidence="ECO:0000250"
FT   DISULFID        10..32
FT                   /evidence="ECO:0000250"
FT   DISULFID        15..24
FT                   /evidence="ECO:0000250"
FT   NON_TER         37
SQ   SEQUENCE   37 AA;  4002 MW;  DD8C85FD78F704CF CRC64;
     DICDDAVAQC SMTLCQLCYN TEICELSVIG SCQPPFS