ARID4_ARATH
ID ARID4_ARATH Reviewed; 747 AA.
AC Q6NQ79; Q9LXL0;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=AT-rich interactive domain-containing protein 4;
DE Short=ARID domain-containing protein 4;
GN Name=ARID4; OrderedLocusNames=At3g43240; ORFNames=F7K15.90;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Carninci P., Hayashizaki Y.,
RA Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA Shinozaki K., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB89045.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL353871; CAB89045.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77778.1; -; Genomic_DNA.
DR EMBL; BT010580; AAQ82841.1; -; mRNA.
DR PIR; T49238; T49238.
DR RefSeq; NP_189910.2; NM_114192.4.
DR PDB; 6LQE; X-ray; 1.90 A; A=673-747.
DR PDB; 6LQF; X-ray; 1.50 A; A=545-747.
DR PDBsum; 6LQE; -.
DR PDBsum; 6LQF; -.
DR AlphaFoldDB; Q6NQ79; -.
DR SMR; Q6NQ79; -.
DR BioGRID; 8721; 5.
DR IntAct; Q6NQ79; 5.
DR STRING; 3702.AT3G43240.1; -.
DR iPTMnet; Q6NQ79; -.
DR PaxDb; Q6NQ79; -.
DR PRIDE; Q6NQ79; -.
DR ProteomicsDB; 246601; -.
DR EnsemblPlants; AT3G43240.1; AT3G43240.1; AT3G43240.
DR GeneID; 823399; -.
DR Gramene; AT3G43240.1; AT3G43240.1; AT3G43240.
DR KEGG; ath:AT3G43240; -.
DR Araport; AT3G43240; -.
DR TAIR; locus:2084731; AT3G43240.
DR eggNOG; ENOG502QQP4; Eukaryota.
DR HOGENOM; CLU_012244_1_0_1; -.
DR InParanoid; Q6NQ79; -.
DR OMA; GSCGEWA; -.
DR OrthoDB; 174616at2759; -.
DR PhylomeDB; Q6NQ79; -.
DR PRO; PR:Q6NQ79; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q6NQ79; baseline and differential.
DR Genevisible; Q6NQ79; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.60; -; 1.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR042293; ARID4.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46694; PTHR46694; 1.
DR Pfam; PF01388; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF46774; SSF46774; 1.
DR SUPFAM; SSF57903; SSF57903; 1.
DR PROSITE; PS51011; ARID; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..747
FT /note="AT-rich interactive domain-containing protein 4"
FT /id="PRO_0000413212"
FT DOMAIN 566..670
FT /note="ARID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00355"
FT ZN_FING 674..730
FT /note="PHD-type"
FT REGION 454..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT TURN 564..566
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 569..582
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 586..588
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 593..596
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 609..617
FT /evidence="ECO:0007829|PDB:6LQF"
FT TURN 618..620
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 622..627
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 630..633
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 635..637
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 650..661
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 663..667
FT /evidence="ECO:0007829|PDB:6LQF"
FT TURN 678..680
FT /evidence="ECO:0007829|PDB:6LQF"
FT STRAND 685..690
FT /evidence="ECO:0007829|PDB:6LQF"
FT TURN 692..694
FT /evidence="ECO:0007829|PDB:6LQF"
FT STRAND 697..699
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 700..702
FT /evidence="ECO:0007829|PDB:6LQF"
FT HELIX 711..715
FT /evidence="ECO:0007829|PDB:6LQF"
FT TURN 725..727
FT /evidence="ECO:0007829|PDB:6LQF"
SQ SEQUENCE 747 AA; 82567 MW; 2468949516ABEC04 CRC64;
MFHGQGFSRN RCNVVAVVSG AELCDTNNQI DGTSHQPKYP FPDLSSSGRL KFQVLNNPTP
EEFQVAVNSS ATDFVYLQGE HSGDSDEVGP LVLGYTDFST PDALVTLFGS TLPTTVYLEL
PNGEELAQAL YSKGVQYVIY WKNVFSKYAA CHFRHSLFSV IQSSCSDTWD VFHVAEASFR
LYCTSDNAVL PSNSNRKMNY EMGPCLLGEP PKIDVVSPEA DELEEENSLE SLPSIKIYDE
DVTVRFLLCG PPCTVDTFLL GSLMDGLNAL LRIEMRGSKL HNRSSAPAPP LQAGTFTRGV
VTMRCDVSTC SSAHISMLVS GNAQTCFSDQ LLENHIKHEV VEKIQLVHSV VNSEETKRGF
SEPRRSASIA CGASVCEVSM QVPTWALQVL RQLAPDVSYR SLVVLGVASI QGLSVASFEK
DDAERLLFFC GQQINDTSNH DALLSKIPNW LTPPLPTRKR SEPCRESKEI ENGGPTSRKI
NVAALRPIPH TRRHKMIPFS GYSEIGRFDG DHTKGSLPMP PKHGASGGTP VTHRKAFSGS
YQRKQIISLN PLPLKKHDCG RAHIQVCSEE EFLRDVMQFL LIRGHTRLVP PGGLAEFPDA
VLNSKRLDLF NLYREVVSRG GFHVGNGINW KGQVFSKMRN HTLTNRMTGV GNTLKRHYET
YLLEYEYAHD DVDGECCLIC RSSTAGDWVN CGSCGEWAHF GCDRRPGLGA FKDYAKTDGL
EYVCPNCSVS NYRKKSQKTS NGGLLVP
