ID   MER2_EUPOC              Reviewed;         154 AA.
AC   O15825;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Mating pheromone 2;
DE   Flags: Precursor;
OS   Euplotoides octocarinatus (Freshwater ciliate) (Euplotes octocarinatus).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Hypotrichia; Euplotida; Euplotidae; Euplotes.
OX   NCBI_TaxID=2716877;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Fl-12;
RA   Bruenen-Nieweler C., Weiligmann J.C., Hansen B., Kuhlmann H.W.,
RA   Moellenbeck M., Heckmann K.;
RT   "The pheromones and pheromone genes of new stocks of the Euplotes
RT   octocarinatus species complex.";
RL   Eur. J. Protist. 34:124-132(1998).
CC   -!- FUNCTION: Mating ciliate pheromones (or gamones) are diffusible
CC       extracellular communication signals that distinguish different
CC       intraspecific classes of cells commonly referred to as 'mating types'.
CC       They prepare the latter for conjugation by changing their cell surface
CC       properties.
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   EMBL; Y15318; CAA75580.1; -; Genomic_DNA.
DR   AlphaFoldDB; O15825; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005186; F:pheromone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR008612; Mating_pheromone_EUPOC.
DR   Pfam; PF05842; Euplotes_phero; 1.
PE   3: Inferred from homology;
KW   Pheromone; Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   PROPEP          17..52
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000008676"
FT   PEPTIDE         53..154
FT                   /note="Mating pheromone 2"
FT                   /id="PRO_0000008677"
SQ   SEQUENCE   154 AA;  17193 MW;  33C94D639581B990 CRC64;
     MKAIFIILAI LMVTQAFKMT SKVNTKLQSQ IQSKFQSKNK LASTFQTSSQ LKDSCLNDPE
     QRFYITGCSN NPVCGDAFDC SATGDDEEKC DAVGQNVIDL FYYFWGTCVN DYASCIMFAA
     TTYNMYSGPE NCGCINQVSY ADWLDYFDCP SFSG