ID   MERD_ACICA              Reviewed;         121 AA.
AC   Q52110; O08091;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=HTH-type transcriptional regulator MerD;
DE   AltName: Full=Mercuric resistance protein MerD;
GN   Name=merD;
OS   Acinetobacter calcoaceticus.
OG   Plasmid pKLH2.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=471;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8302940; DOI=10.1006/plas.1993.1064;
RA   Kholodii G.Y., Lomovskaya O.L., Gorlenko Z.M., Mindlin S.Z., Yurieva O.V.,
RA   Nikiforov V.G.;
RT   "Molecular characterization of an aberrant mercury resistance transposable
RT   element from an environmental Acinetobacter strain.";
RL   Plasmid 30:303-308(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9159519; DOI=10.1046/j.1365-2958.1997.3261688.x;
RA   Yurieva O., Kholodii G., Minakhin L., Gorlenko Z., Kalyaeva E., Mindlin S.,
RA   Nikiforov V.;
RT   "Intercontinental spread of promiscuous mercury-resistance transposons in
RT   environmental bacteria.";
RL   Mol. Microbiol. 24:321-329(1997).
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DR   EMBL; AF213017; AAA19683.1; -; Genomic_DNA.
DR   RefSeq; WP_001277463.1; NZ_MOSW01000200.1.
DR   AlphaFoldDB; Q52110; -.
DR   SMR; Q52110; -.
DR   GeneID; 67375406; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0046689; P:response to mercury ion; IEA:UniProtKB-KW.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR011797; MerD.
DR   InterPro; IPR000551; MerR-type_HTH_dom.
DR   Pfam; PF13411; MerR_1; 1.
DR   PRINTS; PR00040; HTHMERR.
DR   SMART; SM00422; HTH_MERR; 1.
DR   SUPFAM; SSF46955; SSF46955; 1.
DR   TIGRFAMs; TIGR02054; MerD; 1.
DR   PROSITE; PS50937; HTH_MERR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Mercuric resistance; Plasmid; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..121
FT                   /note="HTH-type transcriptional regulator MerD"
FT                   /id="PRO_0000098128"
FT   DOMAIN          3..72
FT                   /note="HTH merR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
FT   DNA_BIND        6..25
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
SQ   SEQUENCE   121 AA;  12966 MW;  0767B816BFF6968B CRC64;
     MSAYTVSRLA LDAGVSVHIV RDYLLRGLLR PVACTTGGYG LFDDTALQRL RFVRAAFEAG
     IGLDALARLC RALDAADGDG ASAQLAVLRQ LVERRREALA SLEMQLAAMP TEPAQHAESL
     P