MERD_ENTAG
ID MERD_ENTAG Reviewed; 121 AA.
AC P0A2Q7; P94703;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 49.
DE RecName: Full=HTH-type transcriptional regulator MerD;
DE AltName: Full=Mercuric resistance protein MerD;
GN Name=merD;
OS Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans).
OG Plasmid pKLH272.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Pantoea; Pantoea agglomerans group.
OX NCBI_TaxID=549;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KH72;
RX PubMed=9159519; DOI=10.1046/j.1365-2958.1997.3261688.x;
RA Yurieva O., Kholodii G., Minakhin L., Gorlenko Z., Kalyaeva E., Mindlin S.,
RA Nikiforov V.;
RT "Intercontinental spread of promiscuous mercury-resistance transposons in
RT environmental bacteria.";
RL Mol. Microbiol. 24:321-329(1997).
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DR EMBL; Y08992; CAA70178.1; -; Genomic_DNA.
DR AlphaFoldDB; P0A2Q7; -.
DR SMR; P0A2Q7; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0046689; P:response to mercury ion; IEA:UniProtKB-KW.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR011797; MerD.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR Pfam; PF13411; MerR_1; 1.
DR PRINTS; PR00040; HTHMERR.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF46955; SSF46955; 1.
DR TIGRFAMs; TIGR02054; MerD; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding; Mercuric resistance; Plasmid; Transcription;
KW Transcription regulation.
FT CHAIN 1..121
FT /note="HTH-type transcriptional regulator MerD"
FT /id="PRO_0000098129"
FT DOMAIN 3..72
FT /note="HTH merR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
FT DNA_BIND 6..25
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
SQ SEQUENCE 121 AA; 13026 MW; BD7C19ACA44C969B CRC64;
MSAYTVSRLA LDAGVSVHIV RDYLLRGLLR PVAYTTGGYG LFDDTALQRL RFVRAAFEAG
IGLDALARLC RALDAADGDG ASAQLAVLRQ LVERRREALA SLEMQLAAMP TEPAQHAESL
P