ID   MERT_SERMA              Reviewed;         116 AA.
AC   P13112;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Mercuric transport protein MerT {ECO:0000250|UniProtKB:P04140};
DE   AltName: Full=Mercury ion transport protein {ECO:0000250|UniProtKB:P04140};
GN   Name=merT {ECO:0000303|PubMed:2666393};
OS   Serratia marcescens.
OG   Plasmid pDU1358.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2666393; DOI=10.1128/jb.171.8.4241-4247.1989;
RA   Nucifora G., Chu L., Silver S., Misra T.K.;
RT   "Mercury operon regulation by the merR gene of the organomercurial
RT   resistance system of plasmid pDU1358.";
RL   J. Bacteriol. 171:4241-4247(1989).
CC   -!- FUNCTION: Involved in mercury resistance. Probably transfers a mercuric
CC       ion from the periplasmic Hg(2+)-binding protein MerP to the cytoplasmic
CC       mercuric reductase MerA. {ECO:0000250|UniProtKB:P04140}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the MerT family. {ECO:0000305}.
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DR   EMBL; M24940; AAA98222.1; -; Genomic_DNA.
DR   RefSeq; WP_001294666.1; NZ_SWIB01000042.1.
DR   AlphaFoldDB; P13112; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015097; F:mercury ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR003457; Transprt_MerT.
DR   Pfam; PF02411; MerT; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Mercuric resistance; Mercury;
KW   Metal-binding; Plasmid; Transmembrane; Transmembrane helix; Transport;
KW   Transposable element.
FT   CHAIN           1..116
FT                   /note="Mercuric transport protein MerT"
FT                   /id="PRO_0000096433"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         24
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000250|UniProtKB:P04140"
FT   BINDING         25
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000250|UniProtKB:P04140"
FT   BINDING         76
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000250|UniProtKB:P04140"
FT   BINDING         82
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000250|UniProtKB:P04140"
SQ   SEQUENCE   116 AA;  12511 MW;  4BE13C204E21A79E CRC64;
     MSEPQNGRGA LFTGGLAAIL ASACCLGPLV LIALGFSGAW IGNLTVLEPY RPIFIGAALV
     ALFFAWRRIY RPAQACKPGD VCAIPQVRAT YKLIFWVVAA LVLVALGFPY VMPFFY