ID   MERT_STAAU              Reviewed;         128 AA.
AC   P08656;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Mercuric transport protein;
DE   AltName: Full=Mercury ion transport protein;
GN   Name=merT;
OS   Staphylococcus aureus.
OG   Plasmid pI258.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3037534; DOI=10.1073/pnas.84.15.5106;
RA   Laddaga R.A., Chu L., Misra T.K., Silver S.;
RT   "Nucleotide sequence and expression of the mercurial-resistance operon from
RT   Staphylococcus aureus plasmid pI258.";
RL   Proc. Natl. Acad. Sci. U.S.A. 84:5106-5110(1987).
CC   -!- FUNCTION: Involved in mercuric transport. Passes a mercury ion from the
CC       MerP protein to the mercuric reductase MerA.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
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DR   EMBL; L29436; AAA98244.1; -; Genomic_DNA.
DR   PIR; D29504; D29504.
DR   RefSeq; WP_001794630.1; NZ_WBTO01000038.1.
DR   RefSeq; YP_006938629.1; NC_013347.1.
DR   AlphaFoldDB; P08656; -.
DR   SMR; P08656; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046689; P:response to mercury ion; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Cell membrane; Membrane; Mercuric resistance; Mercury; Metal-binding;
KW   Plasmid; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..128
FT                   /note="Mercuric transport protein"
FT                   /id="PRO_0000096436"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          101..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        101..115
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         47
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000255"
FT   BINDING         48
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000255"
FT   BINDING         114
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000255"
FT   BINDING         115
FT                   /ligand="Hg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:16793"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   128 AA;  14182 MW;  C9974E2B4A8AFE91 CRC64;
     MYLNQRIKFF LERVVRMMDE NRSKGNRWGV WAFFGILLVP LLVPLLCCAG PILLVALGST
     GIGALFAGAT GNWWLTGIFA ALAIVMIALI LSKLLKNKYN SPEGNGKTKN KTDCCTPPES
     VDRKHETR