ID   ARIR_ECOK1              Reviewed;          88 AA.
AC   A1AA91; Q2LD81;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Regulatory protein AriR;
GN   Name=ariR; OrderedLocusNames=Ecok1_10870; ORFNames=APECO1_280;
OS   Escherichia coli O1:K1 / APEC.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=405955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Johnson T.J., Nolan L.K.;
RT   "Avian pathogenic Escherichia coli strain O1 contains multiple copies of
RT   the sitABCD iron transport system within its genome.";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17293413; DOI=10.1128/jb.01726-06;
RA   Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA   Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT   "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT   shares strong similarities with human extraintestinal pathogenic E. coli
RT   genomes.";
RL   J. Bacteriol. 189:3228-3236(2007).
CC   -!- FUNCTION: Regulates expression of genes involved in acid-resistance and
CC       biofilm formation. May be a non-specific DNA-binding protein that binds
CC       genes and/or intergenic regions via a geometric recognition (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AriR family. {ECO:0000305}.
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DR   EMBL; DQ335213; ABC70493.1; -; Genomic_DNA.
DR   EMBL; CP000468; ABJ00581.1; -; Genomic_DNA.
DR   RefSeq; WP_000888771.1; NC_008563.1.
DR   AlphaFoldDB; A1AA91; -.
DR   SMR; A1AA91; -.
DR   EnsemblBacteria; ABJ00581; ABJ00581; APECO1_280.
DR   KEGG; ecv:APECO1_280; -.
DR   HOGENOM; CLU_164045_1_0_6; -.
DR   OMA; EMVVGMT; -.
DR   Proteomes; UP000008216; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0071468; P:cellular response to acidic pH; IEA:InterPro.
DR   InterPro; IPR024753; AriR.
DR   Pfam; PF10798; YmgB; 1.
PE   3: Inferred from homology;
KW   DNA-binding.
FT   CHAIN           1..88
FT                   /note="Regulatory protein AriR"
FT                   /id="PRO_0000350559"
SQ   SEQUENCE   88 AA;  9696 MW;  E3EDBA8E55110F71 CRC64;
     MLEDTTIHNA ISDKALSSYF RSSGNLLEEE SAVLGQAVTN LMLSGDNVNN KNIILSLIHS
     LETTSDILKA DVIRKTLEIV LRYTADDM