MET24_XENTR
ID MET24_XENTR Reviewed; 353 AA.
AC B1WB06;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Probable methyltransferase-like protein 24 {ECO:0000305};
DE EC=2.1.1.- {ECO:0000305};
DE Flags: Precursor;
GN Name=mettl24;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6; TISSUE=Lung;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable methyltransferase. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
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DR EMBL; BC161568; AAI61568.1; -; mRNA.
DR RefSeq; NP_001120581.1; NM_001127109.1.
DR AlphaFoldDB; B1WB06; -.
DR STRING; 8364.ENSXETP00000036537; -.
DR PaxDb; B1WB06; -.
DR Ensembl; ENSXETT00000046100; ENSXETP00000046100; ENSXETG00000021314.
DR GeneID; 100145735; -.
DR KEGG; xtr:100145735; -.
DR CTD; 728464; -.
DR Xenbase; XB-GENE-5957361; mettl24.
DR eggNOG; ENOG502QRD5; Eukaryota.
DR HOGENOM; CLU_061403_0_0_1; -.
DR InParanoid; B1WB06; -.
DR OMA; TQIACDH; -.
DR OrthoDB; 1540267at2759; -.
DR PhylomeDB; B1WB06; -.
DR TreeFam; TF330614; -.
DR Proteomes; UP000008143; Chromosome 5.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000021314; Expressed in heart and 10 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR026913; METTL24.
DR PANTHER; PTHR32026; PTHR32026; 1.
DR Pfam; PF13383; Methyltransf_22; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase; Reference proteome; Secreted; Signal; Transferase.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..353
FT /note="Probable methyltransferase-like protein 24"
FT /id="PRO_0000343746"
FT REGION 73..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 353 AA; 41243 MW; 70716EFF3003A78A CRC64;
MLGRELRLRW RMCALRLLAI SLGILLCTHF SAELRRRSGP PEKLVVAKVE STARDLNKRA
EEMPSRRQVI YVRRSSSSSK AANPATNRRD NNKPIRWHID LQPWASSSHS LDSEAIRFLR
YITTTQIICS HRIKNGQTDQ SVDASKPWTV CLDEKFNLAH QIRNKQCRVY SLGLGEDDNN
FEVNMASRGC EVHRFDPSIA STQIHEGERL WHHRLSIDWR DPKPAIATHK LHITTKKLGT
ILNEFGHWKI DVLKADMESA EWKILENLIL EGVVEQIGQL IFEIHLHWPG FEVSGNDSSV
VRYWYSLFKE LERKDFKLFY TYKDLSKPQR FLKKEIYNAS SCYILSWVNT RWT