ARL10_MOUSE
ID ARL10_MOUSE Reviewed; 243 AA.
AC Q9QXJ4; Q14C12;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2012, sequence version 2.
DT 03-AUG-2022, entry version 146.
DE RecName: Full=ADP-ribosylation factor-like protein 10;
DE AltName: Full=ADP-ribosylation factor-like membrane-associated protein;
GN Name=Arl10; Synonyms=Arl10a, Arm1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=C57BL/6J;
RA Nehrke K., Silverman P., Pilato J., Kingsley P., Melvin J.E.;
RT "ARM, a novel ADP-ribosylation factor-like membrane associated protein,
RT interacts with the chloride channel ClC3.";
RL Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION.
RX PubMed=15033445; DOI=10.1016/j.bbrc.2004.02.091;
RA Louro R., Nakaya H.I., Paquola A.C.M., Martins E.A.L., da Silva A.M.,
RA Verjovski-Almeida S., Reis E.M.;
RT "Rasl11a, member of a novel small monomeric GTPase gene family, is
RT differentially expressed in prostate tumors.";
RL Biochem. Biophys. Res. Commun. 316:618-627(2004).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Kidney;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000305}.
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DR EMBL; AF205936; AAF20926.1; -; mRNA.
DR EMBL; AC155262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH466546; EDL41145.1; -; Genomic_DNA.
DR EMBL; BC115498; AAI15499.1; -; mRNA.
DR EMBL; BK001711; DAA02253.1; -; mRNA.
DR CCDS; CCDS26530.1; -.
DR RefSeq; NP_064352.2; NM_019968.2.
DR AlphaFoldDB; Q9QXJ4; -.
DR SMR; Q9QXJ4; -.
DR BioGRID; 208179; 1.
DR STRING; 10090.ENSMUSP00000026988; -.
DR iPTMnet; Q9QXJ4; -.
DR PhosphoSitePlus; Q9QXJ4; -.
DR MaxQB; Q9QXJ4; -.
DR PaxDb; Q9QXJ4; -.
DR PRIDE; Q9QXJ4; -.
DR ProteomicsDB; 283171; -.
DR Antibodypedia; 29070; 80 antibodies from 16 providers.
DR Ensembl; ENSMUST00000026988; ENSMUSP00000026988; ENSMUSG00000025870.
DR GeneID; 56795; -.
DR KEGG; mmu:56795; -.
DR UCSC; uc007qoj.2; mouse.
DR CTD; 285598; -.
DR MGI; MGI:1930788; Arl10.
DR VEuPathDB; HostDB:ENSMUSG00000025870; -.
DR eggNOG; KOG0075; Eukaryota.
DR GeneTree; ENSGT00940000160017; -.
DR HOGENOM; CLU_040729_11_0_1; -.
DR InParanoid; Q9QXJ4; -.
DR OMA; QAAYCTI; -.
DR OrthoDB; 1410051at2759; -.
DR PhylomeDB; Q9QXJ4; -.
DR TreeFam; TF105469; -.
DR BioGRID-ORCS; 56795; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Adrm1; mouse.
DR PRO; PR:Q9QXJ4; -.
DR Proteomes; UP000000589; Chromosome 13.
DR RNAct; Q9QXJ4; protein.
DR Bgee; ENSMUSG00000025870; Expressed in embryonic brain and 82 other tissues.
DR ExpressionAtlas; Q9QXJ4; baseline and differential.
DR Genevisible; Q9QXJ4; MM.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR042951; ARL10.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR PANTHER; PTHR47575; PTHR47575; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51417; ARF; 1.
PE 1: Evidence at protein level;
KW GTP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..243
FT /note="ADP-ribosylation factor-like protein 10"
FT /id="PRO_0000207477"
FT BINDING 83..90
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 127..131
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 184..187
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT CONFLICT 130
FT /note="G -> D (in Ref. 1; AAF20926)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 243 AA; 27303 MW; C071554F6CCDB08D CRC64;
MAPRPLGPLV LALGGAAAVL GSVLFILWKA YFGRGRERRW DRGEAWWGAD TARLPQWDEW
EPEDEEDEPA LEELEQREVL VLGLDGSGKS TFLRMLAGKP PVEGHVPTWG FNSVRLPTKN
FEVDLLEIGG SQNLRFYWKE FVNEVDVLVF MVDSTDRLRL PWARQELQKL LDRDPDLPVV
IVANKQDLSG AMNMVELQQE LGLLASYNQR EVFLLAASIA PAGSGFGEPG TVHIWKLLLQ
LLS
