ID   METI_SALTY              Reviewed;         217 AA.
AC   Q8ZRN0;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=D-methionine transport system permease protein MetI;
GN   Name=metI; OrderedLocusNames=STM0246;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for D-
CC       methionine and the toxic methionine analog alpha-methyl-methionine.
CC       Probably responsible for the translocation of the substrate across the
CC       membrane (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; AE006468; AAL19209.1; -; Genomic_DNA.
DR   RefSeq; NP_459250.1; NC_003197.2.
DR   RefSeq; WP_001287486.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZRN0; -.
DR   SMR; Q8ZRN0; -.
DR   STRING; 99287.STM0246; -.
DR   PaxDb; Q8ZRN0; -.
DR   EnsemblBacteria; AAL19209; AAL19209; STM0246.
DR   GeneID; 1251764; -.
DR   KEGG; stm:STM0246; -.
DR   PATRIC; fig|99287.12.peg.260; -.
DR   HOGENOM; CLU_077375_0_1_6; -.
DR   OMA; TFWSAIF; -.
DR   PhylomeDB; Q8ZRN0; -.
DR   BioCyc; SENT99287:STM0246-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR   GO; GO:0048473; P:D-methionine transport; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..217
FT                   /note="D-methionine transport system permease protein MetI"
FT                   /id="PRO_0000060101"
FT   TOPO_DOM        1..19
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        41..54
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        78..92
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        114..151
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        173..185
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        207..217
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          13..204
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   217 AA;  23249 MW;  EC6253BD1D5C6D9A CRC64;
     MSEAMMWLLV RGVWETLAMT FVSGFFGFVI GLPVGVLLYV TRPGQIMENA RLYRSLSAVV
     NIFRSIPFII LLVWMIPFTR IIVGTSIGLQ AAIVPLTVGA APFIARMVEN ALLEIPAGLI
     EASRAMGATP LQIVRKILLP EALPGLVNAA TITLITLVGY SAMGGAVGAG GLGQIGYQYG
     YIGYNATVMN TVLVLLVVLV YLIQLSGDRI VRAVTHK