ID   METI_VIBCH              Reviewed;         225 AA.
AC   Q9KTJ6;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Probable D-methionine transport system permease protein MetI;
GN   Name=metI; OrderedLocusNames=VC_0906;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for D-
CC       methionine. Probably responsible for the translocation of the substrate
CC       across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; AE003852; AAF94068.1; -; Genomic_DNA.
DR   PIR; B82266; B82266.
DR   RefSeq; NP_230553.1; NC_002505.1.
DR   RefSeq; WP_000009571.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KTJ6; -.
DR   SMR; Q9KTJ6; -.
DR   STRING; 243277.VC_0906; -.
DR   DNASU; 2614197; -.
DR   EnsemblBacteria; AAF94068; AAF94068; VC_0906.
DR   GeneID; 57739598; -.
DR   KEGG; vch:VC_0906; -.
DR   PATRIC; fig|243277.26.peg.863; -.
DR   eggNOG; COG2011; Bacteria.
DR   HOGENOM; CLU_077375_0_1_6; -.
DR   OMA; TFWSAIF; -.
DR   BioCyc; VCHO:VC0906-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR   GO; GO:0048473; P:D-methionine transport; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..225
FT                   /note="Probable D-methionine transport system permease
FT                   protein MetI"
FT                   /id="PRO_0000060105"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        62..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          21..212
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   225 AA;  23762 MW;  B4E8FBAC17660927 CRC64;
     MSFNTIAQWF ALNSDLLLTA TWQTLYMVAI AGAVGFALGI PLGVILHTTK KEGLLENLPL
     NRALGAVVNI GRSVPFLVLM VAIIPVTKLI VGTFIGTTAA IVPLTIGAIP FVARLIESAL
     LEVPTGLVEA AQSMGATPLQ IIRKVLLPEA LPTILNSVTI TLVTLVSYSA MAGTVGGGGL
     GDVAIRYGFH RYDITIMAVT VVMLIVLVQI IQSIGDALVR RVDHR