ID   METJ_SHEON              Reviewed;         104 AA.
AC   Q8EA52;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Met repressor {ECO:0000255|HAMAP-Rule:MF_00744};
DE   AltName: Full=Met regulon regulatory protein MetJ {ECO:0000255|HAMAP-Rule:MF_00744};
GN   Name=metJ {ECO:0000255|HAMAP-Rule:MF_00744}; OrderedLocusNames=SO_4057;
OS   Shewanella oneidensis (strain MR-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=211586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MR-1;
RX   PubMed=12368813; DOI=10.1038/nbt749;
RA   Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA   Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A.,
RA   Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA   Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J.,
RA   Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J.,
RA   Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V.,
RA   Smith H.O., Venter J.C., Nealson K.H., Fraser C.M.;
RT   "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT   Shewanella oneidensis.";
RL   Nat. Biotechnol. 20:1118-1123(2002).
CC   -!- FUNCTION: This regulatory protein, when combined with SAM (S-
CC       adenosylmethionine) represses the expression of the methionine regulon
CC       and of enzymes involved in SAM synthesis. {ECO:0000255|HAMAP-
CC       Rule:MF_00744}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00744}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00744}.
CC   -!- DOMAIN: Does not bind DNA by a helix-turn-helix motif.
CC   -!- SIMILARITY: Belongs to the MetJ family. {ECO:0000255|HAMAP-
CC       Rule:MF_00744}.
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DR   EMBL; AE014299; AAN57031.1; -; Genomic_DNA.
DR   RefSeq; NP_719587.1; NC_004347.2.
DR   RefSeq; WP_011073770.1; NZ_CP053946.1.
DR   AlphaFoldDB; Q8EA52; -.
DR   SMR; Q8EA52; -.
DR   STRING; 211586.SO_4057; -.
DR   PaxDb; Q8EA52; -.
DR   GeneID; 58509879; -.
DR   KEGG; son:SO_4057; -.
DR   PATRIC; fig|211586.12.peg.3930; -.
DR   eggNOG; COG3060; Bacteria.
DR   HOGENOM; CLU_142318_0_0_6; -.
DR   OMA; KWNGEYI; -.
DR   OrthoDB; 1738030at2; -.
DR   PhylomeDB; Q8EA52; -.
DR   BioCyc; SONE211586:G1GMP-3754-MON; -.
DR   Proteomes; UP000008186; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00490; Met_repressor_MetJ; 1.
DR   Gene3D; 1.10.140.10; -; 1.
DR   HAMAP; MF_00744; MetJ; 1.
DR   InterPro; IPR002084; Met_repressor_MetJ.
DR   InterPro; IPR023453; Met_repressor_MetJ_dom_sf.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   Pfam; PF01340; MetJ; 1.
DR   SUPFAM; SSF47598; SSF47598; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Cytoplasm; DNA-binding; Methionine biosynthesis;
KW   Reference proteome; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..104
FT                   /note="Met repressor"
FT                   /id="PRO_0000198406"
SQ   SEQUENCE   104 AA;  11959 MW;  9FE7A8DB33C1A9CB CRC64;
     MTEWNGEYIS PYAEHGKKNE QVKKITVSIP LKVLKVLTDE RTRRQVNNLR HATNSELLCE
     AFLHAYTGQP LPDDADLSKE CPDSIPAEAK RLMDEMGIEW EDME