ARLR_STAES
ID ARLR_STAES Reviewed; 219 AA.
AC Q8CP82;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=Response regulator ArlR;
GN Name=arlR; OrderedLocusNames=SE_1100;
OS Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176280;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12228 / FDA PCI 1200;
RX PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT "Genome-based analysis of virulence genes in a non-biofilm-forming
RT Staphylococcus epidermidis strain (ATCC 12228).";
RL Mol. Microbiol. 49:1577-1593(2003).
CC -!- FUNCTION: Member of the two-component regulatory system ArlS/ArlR.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- PTM: Phosphorylated by ArlS. {ECO:0000250}.
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DR EMBL; AE015929; AAO04697.1; -; Genomic_DNA.
DR RefSeq; NP_764655.1; NC_004461.1.
DR RefSeq; WP_001830971.1; NZ_WBME01000002.1.
DR AlphaFoldDB; Q8CP82; -.
DR SMR; Q8CP82; -.
DR STRING; 176280.SE_1100; -.
DR EnsemblBacteria; AAO04697; AAO04697; SE_1100.
DR GeneID; 50018775; -.
DR KEGG; sep:SE_1100; -.
DR PATRIC; fig|176280.10.peg.1075; -.
DR eggNOG; COG0745; Bacteria.
DR HOGENOM; CLU_000445_30_1_9; -.
DR OMA; NIHGEGF; -.
DR Proteomes; UP000001411; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48111; PTHR48111; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; SSF46894; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1..219
FT /note="Response regulator ArlR"
FT /id="PRO_0000293443"
FT DOMAIN 3..116
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DNA_BIND 122..219
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 219 AA; 25412 MW; 800294830BDF48BA CRC64;
MTNILIVEDE QNLARFIELE LTHENYTVDI ENDGKVGLDK ALSKPYDLYI LDLMLPNING
LEICRQIRQK TTTPIIIITA KSETYDKVAG LDYGADDYIV KPFDIEELLA RIRAVLRRQP
DKDVLDINGI IIDKDAFKVT VNGHQLELTK TEYDLLYVLA ENRNHVMQRE QILDHVWGYN
SEVETNVVDV YIRYLRNKLK PFNKEKSIET VRGVGYVIR
