ID   METQ_ECO57              Reviewed;         271 AA.
AC   Q8X8V9;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=D-methionine-binding lipoprotein MetQ;
DE   Flags: Precursor;
GN   Name=metQ; OrderedLocusNames=Z0209, ECs0199;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: This protein is a component of a D-methionine permease, a
CC       binding protein-dependent, ATP-driven transport system. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- MISCELLANEOUS: The MetNIQ system is also to be able to transport the
CC       toxic methionine analog alpha-methyl-methionine. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NlpA lipoprotein family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG54499.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33622.1; -; Genomic_DNA.
DR   PIR; G85504; G85504.
DR   PIR; G90653; G90653.
DR   RefSeq; NP_308226.1; NC_002695.1.
DR   RefSeq; WP_000874227.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X8V9; -.
DR   SMR; Q8X8V9; -.
DR   STRING; 155864.EDL933_0203; -.
DR   EnsemblBacteria; AAG54499; AAG54499; Z0209.
DR   EnsemblBacteria; BAB33622; BAB33622; ECs_0199.
DR   GeneID; 913959; -.
DR   KEGG; ece:Z0209; -.
DR   KEGG; ecs:ECs_0199; -.
DR   PATRIC; fig|386585.9.peg.303; -.
DR   eggNOG; COG1464; Bacteria.
DR   HOGENOM; CLU_067080_0_0_6; -.
DR   OMA; YQDDAES; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004872; Lipoprotein_NlpA.
DR   PANTHER; PTHR30429; PTHR30429; 1.
DR   Pfam; PF03180; Lipoprotein_9; 1.
DR   PIRSF; PIRSF002854; MetQ; 1.
DR   TIGRFAMs; TIGR00363; TIGR00363; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..271
FT                   /note="D-methionine-binding lipoprotein MetQ"
FT                   /id="PRO_0000019740"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   271 AA;  29417 MW;  39D7DA15B5CD2BFB CRC64;
     MAFKFKTFAA VGALIGSLAL VGCGQDEKDP NHIKVGVIVG AEQQVAEVAQ KVAKDKYGLD
     VELVTFNDYV LPNEALSKGD IDANAFQHKP YLDQQLKDRG YKLVAVGNTF VYPIAGYSKK
     IKSLDELQDG SQVAVPNDPT NLGRSLLLLQ KVGLIKLKDG VGLLPTVLDV VENPKNLKIV
     ELEAPQLPRS LDDAQIALAV INTTYASQIG LTPAKNGIFV EDKDSPYVNL IVTREDNKDA
     ENVKKFVQAY QSDEVYEAAN KVFNGGAVKG W