ID   METQ_SALTI              Reviewed;         271 AA.
AC   Q8Z992;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=D-methionine-binding lipoprotein MetQ;
DE   Flags: Precursor;
GN   Name=metQ; OrderedLocusNames=STY0272, t0248;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: This protein is a component of a D-methionine permease, a
CC       binding protein-dependent, ATP-driven transport system. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- MISCELLANEOUS: The MetNIQ system is also to be able to transport the
CC       toxic methionine analog alpha-methyl-methionine. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NlpA lipoprotein family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD08705.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO67977.1; -; Genomic_DNA.
DR   RefSeq; NP_454854.1; NC_003198.1.
DR   RefSeq; WP_000874217.1; NZ_WSUR01000065.1.
DR   AlphaFoldDB; Q8Z992; -.
DR   SMR; Q8Z992; -.
DR   STRING; 220341.16501528; -.
DR   EnsemblBacteria; AAO67977; AAO67977; t0248.
DR   KEGG; stt:t0248; -.
DR   KEGG; sty:STY0272; -.
DR   PATRIC; fig|220341.7.peg.273; -.
DR   eggNOG; COG1464; Bacteria.
DR   HOGENOM; CLU_067080_0_0_6; -.
DR   OMA; YQDDAES; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004872; Lipoprotein_NlpA.
DR   PANTHER; PTHR30429; PTHR30429; 1.
DR   Pfam; PF03180; Lipoprotein_9; 1.
DR   PIRSF; PIRSF002854; MetQ; 1.
DR   TIGRFAMs; TIGR00363; TIGR00363; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Lipoprotein; Membrane; Palmitate;
KW   Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..271
FT                   /note="D-methionine-binding lipoprotein MetQ"
FT                   /id="PRO_0000019741"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   271 AA;  29466 MW;  49B62C4CF96D9613 CRC64;
     MAFKFKTFAA VGALIGSLAL AGCGQDEKDP NHIKVGVIVG AEQQVAEVAQ KVAKEKYGLD
     VELVTFNDYV LPNEALSKGD IDANAFQHKP YLDQQIKDRG YKLVSVGKTF VYPIAGYSKK
     IKSLDELKDG SQVAVPNDPT NLGRSLLLLQ KVGLIKLKDG VSLLPTSLDI VENPKNLKIV
     ELEAPQLPRS LDDAQIALAV INTTYASQIG LTPAKDGIFV EDKDSPYVNL IVTREDNKDA
     ENVKKFVQAY QSDEVYEAAN KVFNGGAVKG W