ID   METQ_SALTY              Reviewed;         271 AA.
AC   Q8ZRN1;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=D-methionine-binding lipoprotein MetQ;
DE   Flags: Precursor;
GN   Name=metQ; OrderedLocusNames=STM0245;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: This protein is a component of a D-methionine permease, a
CC       binding protein-dependent, ATP-driven transport system. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- MISCELLANEOUS: The MetNIQ system is also to be able to transport the
CC       toxic methionine analog alpha-methyl-methionine. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NlpA lipoprotein family. {ECO:0000305}.
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DR   EMBL; AE006468; AAL19208.1; -; Genomic_DNA.
DR   RefSeq; NP_459249.1; NC_003197.2.
DR   RefSeq; WP_000874215.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZRN1; -.
DR   SMR; Q8ZRN1; -.
DR   STRING; 99287.STM0245; -.
DR   PaxDb; Q8ZRN1; -.
DR   PRIDE; Q8ZRN1; -.
DR   EnsemblBacteria; AAL19208; AAL19208; STM0245.
DR   GeneID; 1251763; -.
DR   KEGG; stm:STM0245; -.
DR   PATRIC; fig|99287.12.peg.259; -.
DR   HOGENOM; CLU_067080_0_0_6; -.
DR   OMA; YQDDAES; -.
DR   PhylomeDB; Q8ZRN1; -.
DR   BioCyc; SENT99287:STM0245-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004872; Lipoprotein_NlpA.
DR   PANTHER; PTHR30429; PTHR30429; 1.
DR   Pfam; PF03180; Lipoprotein_9; 1.
DR   PIRSF; PIRSF002854; MetQ; 1.
DR   TIGRFAMs; TIGR00363; TIGR00363; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..271
FT                   /note="D-methionine-binding lipoprotein MetQ"
FT                   /id="PRO_0000019742"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   271 AA;  29436 MW;  3F6D41E14FBDD707 CRC64;
     MAFKFKTFAA VGALIGSLAL AGCGQDEKDP NHIKVGVIVG AEQQVAEVAQ KVAKEKYGLD
     VELVTFNDYV LPNEALSKGD IDANAFQHKP YLDQQIKDRG YKLVSVGKTF VYPIAGYSKK
     IKSLDELKDG SQVAVPNDPT NLGRSLLLLQ KVGLIKLKDG VGLLPTSLDI VENPKNLKIV
     ELEAPQLPRS LDDAQIALAV INTTYASQIG LTPAKDGIFV EDKDSPYVNL IVTREDNKDA
     ENVKKFVQAY QSDEVYEAAN KVFNGGAVKG W