ID   METQ_VIBCH              Reviewed;         269 AA.
AC   Q9KTJ7;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2002, sequence version 2.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Probable D-methionine-binding lipoprotein MetQ;
DE   Flags: Precursor;
GN   Name=metQ; OrderedLocusNames=VC_0905;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: This protein is a component of a D-methionine permease, a
CC       binding protein-dependent, ATP-driven transport system. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NlpA lipoprotein family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF94067.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE003852; AAF94067.1; ALT_INIT; Genomic_DNA.
DR   PIR; A82266; A82266.
DR   RefSeq; NP_230552.2; NC_002505.1.
DR   RefSeq; WP_000672706.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KTJ7; -.
DR   SMR; Q9KTJ7; -.
DR   STRING; 243277.VC_0905; -.
DR   DNASU; 2614196; -.
DR   EnsemblBacteria; AAF94067; AAF94067; VC_0905.
DR   GeneID; 57739597; -.
DR   KEGG; vch:VC_0905; -.
DR   PATRIC; fig|243277.26.peg.862; -.
DR   eggNOG; COG1464; Bacteria.
DR   HOGENOM; CLU_067080_3_0_6; -.
DR   OMA; QDNKAHN; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004872; Lipoprotein_NlpA.
DR   PANTHER; PTHR30429; PTHR30429; 1.
DR   Pfam; PF03180; Lipoprotein_9; 1.
DR   PIRSF; PIRSF002854; MetQ; 1.
DR   TIGRFAMs; TIGR00363; TIGR00363; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..269
FT                   /note="Probable D-methionine-binding lipoprotein MetQ"
FT                   /id="PRO_0000019744"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   269 AA;  29067 MW;  39E2570EE3F184D6 CRC64;
     MKFSLKSLLT IAAAASTLIL AGCGEKAVDN NKVKIGVMAG AEAQVAEVAA KVAKEKYNLD
     VELVTFTDYV TPNAALDDGS IDANAFQHKP YLDKQIADRG YKLAIVGNTF VYPIAGYSKQ
     IKSVDELQDG ARIAVPNDPT NLGRSLLLLQ QQGLLKLRED VGLLATVRDI VENPKKLEIL
     ELDAAQLPRS LDDVALSIIN TTYASSINLT PEKDGIFVEN KESPYVNILV AREANVNAEN
     VQNFKKAYQT DEVAKAASEI FQGGAVKGW