ID   METQ_YERPE              Reviewed;         271 AA.
AC   Q8ZH40; Q0WHX3;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=D-methionine-binding lipoprotein MetQ;
DE   Flags: Precursor;
GN   Name=metQ; OrderedLocusNames=YPO1071, y3106, YP_2778;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: This protein is a component of a D-methionine permease, a
CC       binding protein-dependent, ATP-driven transport system. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- MISCELLANEOUS: The MetNIQ system is also to be able to transport the
CC       toxic methionine analog alpha-methyl-methionine. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NlpA lipoprotein family. {ECO:0000305}.
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DR   EMBL; AL590842; CAL19737.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM86656.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS62962.1; -; Genomic_DNA.
DR   PIR; AG0131; AG0131.
DR   RefSeq; WP_002212159.1; NZ_WUCM01000044.1.
DR   RefSeq; YP_002346115.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZH40; -.
DR   SMR; Q8ZH40; -.
DR   IntAct; Q8ZH40; 4.
DR   STRING; 214092.YPO1071; -.
DR   PaxDb; Q8ZH40; -.
DR   PRIDE; Q8ZH40; -.
DR   DNASU; 1148053; -.
DR   EnsemblBacteria; AAM86656; AAM86656; y3106.
DR   EnsemblBacteria; AAS62962; AAS62962; YP_2778.
DR   GeneID; 57977489; -.
DR   KEGG; ype:YPO1071; -.
DR   KEGG; ypk:y3106; -.
DR   KEGG; ypm:YP_2778; -.
DR   PATRIC; fig|214092.21.peg.1360; -.
DR   eggNOG; COG1464; Bacteria.
DR   HOGENOM; CLU_067080_3_0_6; -.
DR   OMA; YQDDAES; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004872; Lipoprotein_NlpA.
DR   PANTHER; PTHR30429; PTHR30429; 1.
DR   Pfam; PF03180; Lipoprotein_9; 1.
DR   PIRSF; PIRSF002854; MetQ; 1.
DR   TIGRFAMs; TIGR00363; TIGR00363; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..271
FT                   /note="D-methionine-binding lipoprotein MetQ"
FT                   /id="PRO_0000019743"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   271 AA;  29377 MW;  5214CEB05117FCF8 CRC64;
     MSLKFKSIAA ISALIGTLTL VGCGPTEKAP NHIKVGVIVG AEQQVAEVAQ KVAKEKYGLD
     VELVTFNDYV LPNEALSKGD IDLNAFQHKP YLDQQIKDRG YKLVSVGNSF VYPIAGYSKK
     IKSLDELQPG SQVALPNDPT NLGRSLLLLQ SVGLIKLKDG VGLLPTVLDV VENPKNLKLV
     ELEAPQLPRS LDDQQIALAI INTTYASQIG LTPAKDGLFV EDKESPYVNL IVAREDNKDA
     ENVKKFVQAY QSDEVYDAAN KAFNGGAVKG W