MEU14_SCHPO
ID MEU14_SCHPO Reviewed; 335 AA.
AC O94756;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Meiotic expression up-regulated protein 14;
GN Name=meu14; ORFNames=SPBC1347.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBCELLULAR LOCATION.
RC STRAIN=972 / ATCC 24843;
RX PubMed=12759375; DOI=10.1242/jcs.00496;
RA Okuzaki D., Satake W., Hirata A., Nojima H.;
RT "Fission yeast meu14+ is required for proper nuclear division and accurate
RT forespore membrane formation during meiosis II.";
RL J. Cell Sci. 116:2721-2735(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Has a role in nuclear division during meiosis II where it
CC stabilizes the proper segregation of the spindle pole bodies. Also has
CC a role in the formation and extension of the forespore membrane.
CC {ECO:0000269|PubMed:12759375}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, spindle pole body {ECO:0000269|PubMed:12759375}. Nucleus
CC membrane {ECO:0000269|PubMed:12759375}; Peripheral membrane protein
CC {ECO:0000269|PubMed:12759375}; Cytoplasmic side
CC {ECO:0000269|PubMed:12759375}. Prospore membrane
CC {ECO:0000269|PubMed:12759375}.
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DR EMBL; AB016983; BAA32472.1; -; Genomic_DNA.
DR EMBL; CU329671; CAB37434.1; -; Genomic_DNA.
DR PIR; T39391; T39391.
DR RefSeq; NP_596695.1; NM_001022619.2.
DR AlphaFoldDB; O94756; -.
DR SMR; O94756; -.
DR BioGRID; 276438; 9.
DR STRING; 4896.SPBC1347.03.1; -.
DR iPTMnet; O94756; -.
DR PaxDb; O94756; -.
DR EnsemblFungi; SPBC1347.03.1; SPBC1347.03.1:pep; SPBC1347.03.
DR GeneID; 2539892; -.
DR KEGG; spo:SPBC1347.03; -.
DR PomBase; SPBC1347.03; meu14.
DR VEuPathDB; FungiDB:SPBC1347.03; -.
DR eggNOG; ENOG502RCV0; Eukaryota.
DR HOGENOM; CLU_046464_2_1_1; -.
DR InParanoid; O94756; -.
DR OMA; WGEQTGD; -.
DR PhylomeDB; O94756; -.
DR PRO; PR:O94756; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0036286; C:eisosome filament; IBA:GO_Central.
DR GO; GO:0035974; C:meiotic spindle pole body; IDA:PomBase.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0070056; C:prospore membrane leading edge; IDA:PomBase.
DR GO; GO:0070057; C:prospore membrane spindle pole body attachment site; IDA:PomBase.
DR GO; GO:0008289; F:lipid binding; IBA:GO_Central.
DR GO; GO:0031322; P:ascospore-type prospore-specific spindle pole body remodeling; IMP:PomBase.
DR GO; GO:0070941; P:eisosome assembly; IBA:GO_Central.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR GO; GO:0140043; P:lipid droplet localization to prospore membrane leading edge; EXP:PomBase.
DR GO; GO:0006469; P:negative regulation of protein kinase activity; IBA:GO_Central.
DR Gene3D; 1.20.1270.60; -; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR028245; PIL1/LSP1.
DR PANTHER; PTHR31962; PTHR31962; 1.
DR Pfam; PF13805; Pil1; 1.
PE 4: Predicted;
KW Cytoplasm; Cytoskeleton; Meiosis; Membrane; Nucleus; Reference proteome;
KW Sporulation.
FT CHAIN 1..335
FT /note="Meiotic expression up-regulated protein 14"
FT /id="PRO_0000096448"
SQ SEQUENCE 335 AA; 37392 MW; 82C34F749581F0F6 CRC64;
MPKSSNLKMQ RKGSLRENGL VKGLNKNKFS ISKLKELSHA DDSRKSHRII RSGKSSGEAY
KQAGKGLMNL GNHLSDWGAK SSNLSLNDIS DKIGVLVSEL GETEIEFVKA FNENRIKFKA
IRAMEDSIAP SRAHRQRLIS SIEREEERDP LSPKLTDLQN QLVRTEAENL VGEMQLDNTS
REVFKSSFQG LMDAFQLRAQ KQMTLSYYAS QLAELINDEV AYPGDNPAAY SQKYATQIMH
QCVESMARLL APVTSETTEH VGSDCEFTRK SSSSVEFSDH SQDSGDPSQQ NILQVKNVQA
VLSIPEAESY KAQLLSSIAE EQKKKELQAK STVFL
