ID   MEU6_SCHPO              Reviewed;         651 AA.
AC   O94356; Q96WR3;
DT   20-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Meiotic expression up-regulated protein 6;
GN   Name=meu6; ORFNames=SPBC428.07;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 384-651.
RC   STRAIN=CD16-1;
RX   PubMed=11376151; DOI=10.1093/nar/29.11.2327;
RA   Watanabe T., Miyashita K., Saito T.T., Yoneki T., Kakihara Y.,
RA   Nabeshima K., Kishi Y.A., Shimoda C., Nojima H.;
RT   "Comprehensive isolation of meiosis-specific genes identifies novel
RT   proteins and unusual non-coding transcripts in Schizosaccharomyces pombe.";
RL   Nucleic Acids Res. 29:2327-2337(2001).
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DR   EMBL; CU329671; CAA22282.1; -; Genomic_DNA.
DR   EMBL; AB054317; BAB60883.1; -; mRNA.
DR   PIR; T40459; T40459.
DR   RefSeq; NP_595185.1; NM_001021093.2.
DR   AlphaFoldDB; O94356; -.
DR   SMR; O94356; -.
DR   BioGRID; 277296; 9.
DR   STRING; 4896.SPBC428.07.1; -.
DR   iPTMnet; O94356; -.
DR   MaxQB; O94356; -.
DR   PaxDb; O94356; -.
DR   PRIDE; O94356; -.
DR   EnsemblFungi; SPBC428.07.1; SPBC428.07.1:pep; SPBC428.07.
DR   GeneID; 2540776; -.
DR   KEGG; spo:SPBC428.07; -.
DR   PomBase; SPBC428.07; meu6.
DR   VEuPathDB; FungiDB:SPBC428.07; -.
DR   eggNOG; ENOG502RPAT; Eukaryota.
DR   HOGENOM; CLU_479927_0_0_1; -.
DR   InParanoid; O94356; -.
DR   OMA; FAKRFFY; -.
DR   PRO; PR:O94356; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0008289; F:lipid binding; ISM:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR039712; Meu6.
DR   InterPro; IPR039483; Meu6_PH_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR42073; PTHR42073; 1.
DR   Pfam; PF15406; PH_6; 1.
DR   SMART; SM00233; PH; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Meiosis; Reference proteome.
FT   CHAIN           1..651
FT                   /note="Meiotic expression up-regulated protein 6"
FT                   /id="PRO_0000096455"
FT   DOMAIN          194..261
FT                   /note="PH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT   REGION          1..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          365..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          468..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          587..630
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..33
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..52
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..387
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        406..430
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        473..489
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..514
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        587..605
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   651 AA;  71164 MW;  AD50FBFE1102DEB6 CRC64;
     MSYEGREERP EQIAEPTFEN VSEHNEHDSG SAEAQVETLE VPLSNETDND DATENAVPAE
     VQAPEEPKEP ETVDNIDPAD DDPNSVAAPK VEEKKSKKKA KDEKPLTYTT GGYLYCRSNG
     LIPHVMKRYF YMLEGPMSMD LLDHYYKKHF HGTLQGNPTE PSLASEQMHD SDADSLFQSA
     NDHLNRIAKA TQDCRGLLFY SKSQSTSVPS GIINLTDAVS IEPGTGNKFT INFNNGKSET
     LEALDPESKN TWITDLKNAI AKKKETKDKI KELRAYNDTL KRLGKLAARS GPSASETFRY
     FLPMLSNGRD AKKSSSKSHG GKQNNSVAKD GLFDFFQNMI KGKTPQNDTA SPIDNETSAD
     PVDTTVEAQS VEVPENETNQ IPTTEEHFPA TTEEVAPASE EKPATGPAEE STSTQNVEQA
     STQNDNGTPI GQIADAIEED VKGTAQSVEQ AFIEETDIAL PDIALPDVAT PTADDQDPST
     AATNEESVVS NEDRTSKKAG KKHHRHHKKK KGGNKRVFGF KLHKYAKPTK SVKTLQADPS
     LEFAKAGFEI FPSNLSKKLS GLVQKKVHKK FDKDGRLKEI SQFSKTTIKP ETPLTPTTTP
     TPRTAAQEDP AEETTDALAS AEGENNQMPQ VLETEAAPSI ASEGRSITVN A