MEX1_ARATH
ID MEX1_ARATH Reviewed; 415 AA.
AC Q9LF50; Q9SPJ2; Q9SPJ3;
DT 02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 02-FEB-2004, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Maltose excess protein 1, chloroplastic;
DE AltName: Full=Root cap protein 1;
DE Flags: Precursor;
GN Name=MEX1; Synonyms=RCP1; OrderedLocusNames=At5g17520; ORFNames=K3M16.90;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia, and cv. No-0;
RX PubMed=10536027; DOI=10.1073/pnas.96.22.12941;
RA Tsugeki R., Fedoroff N.V.;
RT "Genetic ablation of root cap cells in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 96:12941-12946(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=14704427; DOI=10.1126/science.1091811;
RA Niittylae T., Messerli G., Trevisan M., Chen J., Smith A.M., Zeeman S.C.;
RT "A previously unknown maltose transporter essential for starch degradation
RT in leaves.";
RL Science 303:87-89(2004).
CC -!- FUNCTION: Probable maltose transporter. Essential for the conversion of
CC starch to sucrose in leaves at night, probably via the export of
CC maltose from the chloroplast. Required for root cap cells formation.
CC {ECO:0000269|PubMed:14704427}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000269|PubMed:14704427}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:14704427}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves and roots. Expressed in root
CC cap cells. {ECO:0000269|PubMed:10536027, ECO:0000269|PubMed:14704427}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC01896.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF168390; AAF04350.1; -; mRNA.
DR EMBL; AF168391; AAF04351.1; -; Genomic_DNA.
DR EMBL; AL391150; CAC01896.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED92436.1; -; Genomic_DNA.
DR EMBL; AY056187; AAL07036.1; -; mRNA.
DR EMBL; AY096715; AAM20349.1; -; mRNA.
DR EMBL; AY084279; AAM60870.1; -; mRNA.
DR PIR; T51478; T51478.
DR RefSeq; NP_568349.1; NM_121758.4.
DR AlphaFoldDB; Q9LF50; -.
DR STRING; 3702.AT5G17520.1; -.
DR TCDB; 2.A.84.1.1; the chloroplast maltose exporter (mex) family.
DR iPTMnet; Q9LF50; -.
DR PaxDb; Q9LF50; -.
DR PRIDE; Q9LF50; -.
DR EnsemblPlants; AT5G17520.1; AT5G17520.1; AT5G17520.
DR GeneID; 831618; -.
DR Gramene; AT5G17520.1; AT5G17520.1; AT5G17520.
DR KEGG; ath:AT5G17520; -.
DR Araport; AT5G17520; -.
DR TAIR; locus:2157492; AT5G17520.
DR eggNOG; ENOG502QTKC; Eukaryota.
DR HOGENOM; CLU_049521_0_0_1; -.
DR InParanoid; Q9LF50; -.
DR OrthoDB; 1459527at2759; -.
DR PhylomeDB; Q9LF50; -.
DR BioCyc; ARA:AT5G17520-MON; -.
DR BioCyc; MetaCyc:AT5G17520-MON; -.
DR PRO; PR:Q9LF50; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LF50; baseline and differential.
DR Genevisible; Q9LF50; AT.
DR GO; GO:0009941; C:chloroplast envelope; IDA:TAIR.
DR GO; GO:0009706; C:chloroplast inner membrane; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0005363; F:maltose transmembrane transporter activity; IDA:TAIR.
DR GO; GO:0005975; P:carbohydrate metabolic process; IMP:TAIR.
DR GO; GO:0000023; P:maltose metabolic process; IMP:TAIR.
DR GO; GO:0009624; P:response to nematode; IEP:TAIR.
DR GO; GO:0005983; P:starch catabolic process; IMP:TAIR.
DR InterPro; IPR034628; MEX1/MEX1-like.
DR PANTHER; PTHR34809; PTHR34809; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Maltose metabolism; Membrane; Plastid; Plastid inner membrane;
KW Reference proteome; Transit peptide; Transmembrane; Transmembrane helix;
KW Transport.
FT TRANSIT 1..?
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN ?..415
FT /note="Maltose excess protein 1, chloroplastic"
FT /id="PRO_0000021684"
FT TRANSMEM 139..159
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 176..196
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..306
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 322..342
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 345..365
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 373..393
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT REGION 74..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 3
FT /note="G -> A (in Ref. 1; AAF04351 and 5; AAM60870)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 415 AA; 45280 MW; B3D9DC21CF42769A CRC64;
MEGKAIATSL GGDRVLIFPC SPRSSFVFTS RLSSLPLKRA SIGGAVSCSG VNGLTRWNSI
VSTRRLVPVR SINSESDSDS DFPHENQQGN PGLGKFKEYQ EWDSWTAKFS GGANIPFLML
QLPQIILNTQ NLLAGNNTAL SAVPWLGMLT GLLGNLSLLS YFAKKREKEA AVVQTLGVVS
THIVLAQLTM AEAMPIQYFV ATSAVVTIGL IVNCLYYFGK LSKTVWQLWE DVITIGGLSV
LPQIMWSTFV PLVPNSILPG TTAFGIAVAA IIMARTGKLS EKGVRFVGSL SGWTATLMFM
WMPVSQMWTN FLNPDNIKGL SSITMLLSMM GNGLMIPRAL FIRDLMWLTG SLWATLFYGY
GNILCLYLVN CTSQSFFVAA TIGLISWIGL ALWRDAVAYG HNSPFRSLKE LVFGP
