MEX1_DROME
ID MEX1_DROME Reviewed; 83 AA.
AC P23487; Q9VUP7;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1991, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Protein midgut expression 1;
GN Name=mex1; ORFNames=CG7936;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, TISSUE SPECIFICITY, AND
RP DEVELOPMENTAL STAGE.
RC STRAIN=Oregon-R;
RX PubMed=1985021; DOI=10.1016/0012-1606(91)90068-e;
RA Schulz R.A., Xie X., Andres A.J., Galewsky S.;
RT "Endoderm-specific expression of the Drosophila mex1 gene.";
RL Dev. Biol. 143:206-211(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Embryo;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- FUNCTION: Involved in morphogenesis and development.
CC {ECO:0000269|PubMed:1985021}.
CC -!- TISSUE SPECIFICITY: Endoderm-specific pattern of expression during
CC embryogenesis; anterior and posterior midgut primordia.
CC {ECO:0000269|PubMed:1985021}.
CC -!- DEVELOPMENTAL STAGE: Expressed during embryogenesis starting at 9 hours
CC of development. {ECO:0000269|PubMed:1985021}.
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DR EMBL; X58286; CAA41224.2; -; Genomic_DNA.
DR EMBL; M63626; AAA28685.1; -; Genomic_DNA.
DR EMBL; AE014296; AAF49628.1; -; Genomic_DNA.
DR EMBL; AY071615; AAL49237.1; -; mRNA.
DR PIR; A49763; A49763.
DR RefSeq; NP_001261880.1; NM_001274951.1.
DR RefSeq; NP_524086.1; NM_079362.4.
DR AlphaFoldDB; P23487; -.
DR BioGRID; 64997; 1.
DR DIP; DIP-19325N; -.
DR IntAct; P23487; 7.
DR STRING; 7227.FBpp0292798; -.
DR PaxDb; P23487; -.
DR DNASU; 39677; -.
DR EnsemblMetazoa; FBtr0075602; FBpp0075355; FBgn0004228.
DR EnsemblMetazoa; FBtr0334084; FBpp0306209; FBgn0004228.
DR GeneID; 39677; -.
DR KEGG; dme:Dmel_CG7936; -.
DR CTD; 39677; -.
DR FlyBase; FBgn0004228; mex1.
DR VEuPathDB; VectorBase:FBgn0004228; -.
DR eggNOG; ENOG502TCVT; Eukaryota.
DR HOGENOM; CLU_194019_0_0_1; -.
DR InParanoid; P23487; -.
DR OrthoDB; 1606326at2759; -.
DR PhylomeDB; P23487; -.
DR BioGRID-ORCS; 39677; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 39677; -.
DR PRO; PR:P23487; -.
DR Proteomes; UP000000803; Chromosome 3L.
DR Bgee; FBgn0004228; Expressed in midgut and 27 other tissues.
DR ExpressionAtlas; P23487; baseline and differential.
DR Genevisible; P23487; DM.
PE 2: Evidence at transcript level;
KW Developmental protein; Reference proteome.
FT CHAIN 1..83
FT /note="Protein midgut expression 1"
FT /id="PRO_0000096456"
SQ SEQUENCE 83 AA; 9424 MW; 3C5EFBFF8BA8E2A0 CRC64;
MCNALCECLK CPGKVVCCCC SCACKMLLSI VFSALLMVVV IGLIVYFTVF YHKDKNTDEV
QKQVAQLTPI VKRSIRDYFN KEY
