ID   MF13A_BOVIN             Reviewed;         517 AA.
AC   Q58CT4;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Transmembrane protein 180 {ECO:0000250|UniProtKB:Q14CX5};
DE   AltName: Full=Major facilitator superfamily domain-containing 13A {ECO:0000250|UniProtKB:Q14CX5};
GN   Name=MFSD13A {ECO:0000250|UniProtKB:Q14CX5};
GN   Synonyms=TMEM180 {ECO:0000250|UniProtKB:Q14CX5};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Basal ganglia;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BT021863; AAX46710.1; -; mRNA.
DR   EMBL; BC119894; AAI19895.1; -; mRNA.
DR   RefSeq; NP_001014925.1; NM_001014925.1.
DR   RefSeq; XP_005225583.1; XM_005225526.3.
DR   RefSeq; XP_005225584.1; XM_005225527.3.
DR   RefSeq; XP_010818189.1; XM_010819887.2.
DR   RefSeq; XP_010818190.1; XM_010819888.2.
DR   AlphaFoldDB; Q58CT4; -.
DR   SMR; Q58CT4; -.
DR   STRING; 9913.ENSBTAP00000028052; -.
DR   PaxDb; Q58CT4; -.
DR   Ensembl; ENSBTAT00000028052; ENSBTAP00000028052; ENSBTAG00000021065.
DR   Ensembl; ENSBTAT00000075709; ENSBTAP00000057913; ENSBTAG00000021065.
DR   GeneID; 514370; -.
DR   KEGG; bta:514370; -.
DR   CTD; 79847; -.
DR   VEuPathDB; HostDB:ENSBTAG00000021065; -.
DR   VGNC; VGNC:31434; MFSD13A.
DR   eggNOG; ENOG502QSW5; Eukaryota.
DR   GeneTree; ENSGT00940000160317; -.
DR   HOGENOM; CLU_034985_0_0_1; -.
DR   InParanoid; Q58CT4; -.
DR   OMA; FVCMNLV; -.
DR   OrthoDB; 1041483at2759; -.
DR   TreeFam; TF313122; -.
DR   Proteomes; UP000009136; Chromosome 26.
DR   Bgee; ENSBTAG00000021065; Expressed in Ammon's horn and 104 other tissues.
DR   ExpressionAtlas; Q58CT4; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR040035; TMEM180.
DR   PANTHER; PTHR28658; PTHR28658; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..517
FT                   /note="Transmembrane protein 180"
FT                   /id="PRO_0000256223"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        306..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        332..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        401..421
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        466..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   517 AA;  57198 MW;  32B585626DA35972 CRC64;
     MRLGGPWAWL LGLPTAVVYG SLALFVSVLH NVFLLYYVDT FVSVYKIDKA AFWVGETVFL
     LWNSLNDPLF GWLSDRQFLS SQPRSGAGLS SRAVVLARVR ALGWHGPLLA LSFLAFWVPW
     APAGLQFLLC LCLYDGFLTL VDLHHHALLA DLALSAHDRT HLNFYCSLFS AAGSLSVFAS
     YAFWNKEDFS SFRAFCLALA TGSGLGFVGA ARLLRRRVEA AGREPGCPAM AVNDGLCEEE
     LLVGGEEAGS ITLGQYLQQL ARHRNFLWFV GMDLVQVFHC HFNSNFFPLF LEHLLSDHIS
     LSTGSFLLGI SYVAPHLNNL YFLPLCRRWG VYAVVRGLFL LKLGLSLLML LAGPDHPGLL
     CLFIASNRVF TEGTCKLLTL VVTDLVDEDL VLNHRKQAAS ALLFGMVALV TKPGQTFAPL
     LGTWLLCFYT GHDLFQQHPP APVGSAQPWP EPPAPPPAQA PPLRQGCFYL LVLVPIACAL
     LQLFTWSQFT LHGRRLHMVK AQRQSLSRAQ TLDVKMV