ID   MF13A_CHICK             Reviewed;         509 AA.
AC   Q5ZKJ5;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Transmembrane protein 180 {ECO:0000250|UniProtKB:Q14CX5};
DE   AltName: Full=Major facilitator superfamily domain-containing 13A {ECO:0000250|UniProtKB:Q14CX5};
GN   Name=MFSD13A {ECO:0000250|UniProtKB:Q14CX5};
GN   Synonyms=TMEM180 {ECO:0000250|UniProtKB:Q14CX5}; ORFNames=RCJMB04_10g6;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AJ720089; CAG31748.1; -; mRNA.
DR   RefSeq; NP_001026403.1; NM_001031232.1.
DR   AlphaFoldDB; Q5ZKJ5; -.
DR   SMR; Q5ZKJ5; -.
DR   STRING; 9031.ENSGALP00000013030; -.
DR   PaxDb; Q5ZKJ5; -.
DR   GeneID; 423861; -.
DR   KEGG; gga:423861; -.
DR   CTD; 79847; -.
DR   VEuPathDB; HostDB:geneid_423861; -.
DR   eggNOG; ENOG502QSW5; Eukaryota.
DR   HOGENOM; CLU_034985_0_0_1; -.
DR   InParanoid; Q5ZKJ5; -.
DR   OrthoDB; 1041483at2759; -.
DR   PhylomeDB; Q5ZKJ5; -.
DR   TreeFam; TF313122; -.
DR   PRO; PR:Q5ZKJ5; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR040035; TMEM180.
DR   PANTHER; PTHR28658; PTHR28658; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..509
FT                   /note="Transmembrane protein 180"
FT                   /id="PRO_0000256226"
FT   TRANSMEM        15..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        261..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        327..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        458..478
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   509 AA;  58075 MW;  B31AB77C80DB2592 CRC64;
     MGLRLLACLF HLPTAVIYGS LSLFVSILHN VFLLYYVDTF VSVYKIDKLS FWIGETVFLI
     WNSLNDPLFG WLSDRVFLST QQPGAEISSP EVVLKRLRAL SHNGPLFAIS FLAFWVAWAH
     PGLQFLLCLC MYDSFLTMVD LHHNALLADL AVSAKDRTSL NFYCSFFSAI GSLSVFMSYA
     VWNKEDFFSF RIFCIVLAFC SIVGFTLSTQ LLRQRFETDG KAKWDQESTL KELYIEKLSV
     PQEKRITLVE YLQQLSRHRN FLWFVCMNLI QVFHCHFNSN FFPLFLEHLL SDKISVSTGS
     FLLGISYIAP HLNNLYFLSL CRRWGVYAVV RGLFFLKLAL SVVMLLAGPD QVYLLCIFIA
     SNRVFTEGTC KLLNLVVTDL VDEDLVLNRR KQAASALLFG MVALVTKPGQ TFAPLIGTWL
     LCVYTGYDIF QRNPLSNVVS AQPKLESDTI LEPTLRQGCF YLLVFVPITC ALLQLLSWTQ
     FSLHGKRLQM VKAQRQGLMQ GRAPEIKMI