ID   MF14B_BOVIN             Reviewed;         502 AA.
AC   A4IF94;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Hippocampus abundant transcript-like protein 1 {ECO:0000250|UniProtKB:Q5SR56};
DE   AltName: Full=Major facilitator superfamily domain-containing 14B {ECO:0000250|UniProtKB:Q5SR56};
GN   Name=MFSD14B {ECO:0000250|UniProtKB:Q5SR56};
GN   Synonyms=HIATL1 {ECO:0000250|UniProtKB:Q5SR56};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; BC134465; AAI34466.1; -; mRNA.
DR   RefSeq; NP_001077131.1; NM_001083662.2.
DR   AlphaFoldDB; A4IF94; -.
DR   SMR; A4IF94; -.
DR   STRING; 9913.ENSBTAP00000004062; -.
DR   PaxDb; A4IF94; -.
DR   PRIDE; A4IF94; -.
DR   Ensembl; ENSBTAT00000004062; ENSBTAP00000004062; ENSBTAG00000003124.
DR   GeneID; 510635; -.
DR   KEGG; bta:510635; -.
DR   CTD; 84641; -.
DR   VEuPathDB; HostDB:ENSBTAG00000003124; -.
DR   VGNC; VGNC:50087; MFSD14B.
DR   eggNOG; KOG2816; Eukaryota.
DR   GeneTree; ENSGT00940000156081; -.
DR   HOGENOM; CLU_001265_10_5_1; -.
DR   InParanoid; A4IF94; -.
DR   OMA; IRPVSWG; -.
DR   OrthoDB; 763423at2759; -.
DR   TreeFam; TF313511; -.
DR   Proteomes; UP000009136; Chromosome 8.
DR   Bgee; ENSBTAG00000003124; Expressed in monocyte and 104 other tissues.
DR   ExpressionAtlas; A4IF94; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   InterPro; IPR001958; Tet-R_TetA/multi-R_MdtG.
DR   Pfam; PF07690; MFS_1; 1.
DR   PRINTS; PR01035; TCRTETA.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..502
FT                   /note="Hippocampus abundant transcript-like protein 1"
FT                   /id="PRO_0000375848"
FT   TOPO_DOM        1..46
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        68..79
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        101..108
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        130..131
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        153..165
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        187..193
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        215..248
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        270..278
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        300..316
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        317..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        338
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        360..384
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        385..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        406..425
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        426..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        447..502
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   502 AA;  54144 MW;  1216547BB403C425 CRC64;
     MNAEPPEEKA ASEAEAGAMP EKRAGSRAAG GNSLQGFGRP SVYHAAIVIF LEFFAWGLLT
     TSMLTVLHET FPQHTFLMNG LIQGVKGLLS FLSAPLIGAL SDVWGRKPFL LGTVFFTCFP
     IPLMRISPWW YFAMISISGV FSVTFSVIFA YVADVTQEHE RSTAYGWVSA TFAASLVSSP
     AIGAYLSASY GDSLVVLVAT VVALLDICFI LLAVPESLPE KMRPLSWGAR ISWKQADPFA
     SLKKVGKDST ILLICITVFL SYLPEAGQYS SFFLYLRQVI GFGSIKIAAF IAMVGILSIV
     AQTVFLTSLM RSLGNKNTVL LGLGFQMFQL AWYGFGSQAW MMWAAGIVAA VSSITFPAVS
     TLVSQNADSN QQGVAQGIIT GIRGLCNGLG PALYGFIFYM FHVELTELEP ELISNNAALQ
     GAVIPGPPFL FGACIVFMSF LVAVFIPEYS KGGIQKHSNS ISGSLANTPE RGSDEDIEPL
     LQDSSIWELS SLEEPGHQCT EL