ID   MF6LA_XENLA             Reviewed;         609 AA.
AC   Q68EU6;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Major facilitator superfamily domain-containing protein 6-like protein A;
GN   Name=mfsd6l-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC080104; AAH80104.1; -; mRNA.
DR   RefSeq; NP_001087560.1; NM_001094091.1.
DR   RefSeq; XP_018093026.1; XM_018237537.1.
DR   RefSeq; XP_018093027.1; XM_018237538.1.
DR   AlphaFoldDB; Q68EU6; -.
DR   DNASU; 447384; -.
DR   GeneID; 447384; -.
DR   KEGG; xla:447384; -.
DR   CTD; 447384; -.
DR   Xenbase; XB-GENE-5841523; mfsd6l.S.
DR   OMA; GQLDCFL; -.
DR   OrthoDB; 453672at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 447384; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR024989; MFS_assoc_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF12832; MFS_1_like; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..609
FT                   /note="Major facilitator superfamily domain-containing
FT                   protein 6-like protein A"
FT                   /id="PRO_0000321947"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        340..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        420..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        452..472
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        475..495
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        513..535
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        541..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          201..241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..235
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   609 AA;  68314 MW;  307EE8A1125EE8DF CRC64;
     MSSTKQWDIS KALTVATLFY FFHNVGKFCL MPFLTLYFRQ LGLGAPLVGI IFGFKHAVHL
     LWAPLCSFLA KNHHKQRFFI MTSLLLSAGV GSLFAYYPPL DKNIVSLFCN TSMPWKEQLN
     PPIDISVSVD ENLNTTYAAP TDHQTTTGAL NTLPSSVGKL ATDPAMTSLD LEITTHQRFT
     DQFPVTSNTI LEHQTKNVLG SGKAQKVMSS KSAASNSKQR SSLNNHTSPY ATHPNVSHHP
     SIHERKVRDI GIDFTDNSLD PQHKIFLIVL VLVIIWEILA APLEWIADDS LYEYLDFVDA
     TDRHGKLWIW GYLGASMGSI FITFLVDNLN CFVIYDIPRV FFHFFCYGGF LIGTLFLSTL
     YPIHVSKKTE HSNKTVKALG FLGSDGRIVL TALTVFLLGA VGSTTQNFLF WQMQDVGSSE
     LYMGLSIAVG LLSELTLYFF RNKLLKIFTF KWMVALGLFS LGVQCLYYSF LWAPWSVLAI
     QILNAFSSGV IWWAINSQVV DLASPGTERS LQLALRWLAY GCGSSTGSFA SGFIISRFSL
     AVLYQACCIT LLLWIIIFLL VQPKLPNTKK INYSRLLAAD NSDMSDSDEE QDRDWLVTAM
     KDENSNRNW