ID   MF6LB_XENLA             Reviewed;         614 AA.
AC   Q5XGZ9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Major facilitator superfamily domain-containing protein 6-like protein B;
GN   Name=mfsd6l-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC       {ECO:0000305}.
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DR   EMBL; BC084277; AAH84277.1; -; mRNA.
DR   RefSeq; NP_001088272.1; NM_001094803.1.
DR   AlphaFoldDB; Q5XGZ9; -.
DR   DNASU; 495104; -.
DR   GeneID; 495104; -.
DR   KEGG; xla:495104; -.
DR   CTD; 495104; -.
DR   OMA; RFFIMAS; -.
DR   OrthoDB; 453672at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 495104; Expressed in oocyte and 17 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR024989; MFS_assoc_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF12832; MFS_1_like; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..614
FT                   /note="Major facilitator superfamily domain-containing
FT                   protein 6-like protein B"
FT                   /id="PRO_0000321948"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        312..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        457..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        480..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        520..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        546..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          177..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..193
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..239
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   614 AA;  68973 MW;  95D6DEC70346D63C CRC64;
     MSSTKQWDIS KALAVATLFH FFHNVGKFCL MPFLTLYFRQ LGLGASLVGI IIGFKHAVHL
     LWAPLCSFLA KSHRKRRFFI MASLLLSAGA GGLFAFYPPL DKNIVSLFCN TSMPWKEQLN
     PPIDISVFVD ENISTTYATP TNHQTTNGEF NTFPSSVAEV AIDTTMASSL DMKTTTHQRF
     TDQFPSSSPL TRNKRLEHQT RKVLGSGKAQ KANSSKSSAS NSKQRSSLNN QTAPFATHPN
     VSHRPSIHER KVRDISIDFT DSFLDPKHKI FLIVLAMVII WEILAAPLEW IADDSLYEYL
     DFVDATDRHG KLWIWGYLGA SMGSIFITFL IDNLNCFVIF DIPRVSFHFF CYGGFLISTF
     FLSTLYPVHV SKKTEHSNKT VKALGFLGSD GRIVLTALTV FVLGAVGSTI QNFLFWQMQD
     IGSNELYMGL SIAAGLLSEL ALYFFRNKLL KTLTFKWMVV LGLLSLGIQF LYYSFLWTPW
     SVVAIQILNA FSSGVIWWAI NSQVVDVASP GTERSLQLTL RWLAYGCGSS AGSFASGFII
     SRFSLAVLYQ ACCITLLTWI VIFLLVQPKL PNIKKINYSR LLAADNSDMS DSDEEQDRDW
     LVTAMKDENS NRKW