ID   MFAP_LACKL              Reviewed;         125 AA.
AC   P06648;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Mating factor alpha;
DE   AltName: Full=Alpha mating pheromone;
DE   Contains:
DE     RecName: Full=Alpha-mating pheromone;
DE   Contains:
DE     RecName: Full=Mating factor alpha;
DE   Flags: Precursor;
OS   Lachancea kluyveri (Yeast) (Saccharomyces kluyveri).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=4934;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NBRC 1894 / Ks-133(-);
RX   PubMed=3627991; DOI=10.1093/nar/15.15.6303;
RA   Egel-Mitani M., Hansen M.T.;
RT   "Nucleotide sequence of the gene encoding the Saccharomyces kluyveri alpha
RT   mating pheromone.";
RL   Nucleic Acids Res. 15:6303-6303(1987).
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DR   EMBL; Y00385; CAA68455.1; -; Genomic_DNA.
DR   PIR; A29120; A29120.
DR   AlphaFoldDB; P06648; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0000772; F:mating pheromone activity; IEA:InterPro.
DR   GO; GO:0007618; P:mating; IEA:InterPro.
DR   GO; GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IEA:InterPro.
DR   InterPro; IPR016326; Mating_factor_a.
DR   InterPro; IPR006742; Mating_factor_alpha_C.
DR   InterPro; IPR008675; Mating_factor_alpha_N.
DR   Pfam; PF04648; MF_alpha; 2.
DR   Pfam; PF05436; MF_alpha_N; 1.
DR   PIRSF; PIRSF001866; Mating_factor_alpha; 1.
PE   4: Predicted;
KW   Glycoprotein; Pheromone; Signal.
FT   SIGNAL          1..22
FT   CHAIN           23..125
FT                   /note="Alpha-mating pheromone"
FT                   /id="PRO_0000021704"
FT   PEPTIDE         92..104
FT                   /note="Mating factor alpha"
FT                   /id="PRO_0000021705"
FT   PEPTIDE         113..125
FT                   /note="Mating factor alpha"
FT                   /id="PRO_0000021706"
FT   CARBOHYD        57
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        67
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   125 AA;  13925 MW;  3ABB7E8C86B81AA1 CRC64;
     MKLFTTLSAS LIFIHSLGST RAAPVTGDES SVEIPEESLI GFLDLAGDDI SVFPVSNETH
     YGLMLVNSTI VNLARSESAN FKGKREADAE PWHWLSFSKG EPMYKREADA EPWHWLSFSK
     GEPMY