MFR1L_DANRE
ID MFR1L_DANRE Reviewed; 309 AA.
AC Q7T3E8;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Mitochondrial fission regulator 1-like;
GN Name=mtfr1l; Synonyms=fam54b; ORFNames=zgc:63922;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-253, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RC TISSUE=Embryo;
RX PubMed=18307296; DOI=10.1021/pr700667w;
RA Lemeer S., Pinkse M.W.H., Mohammed S., van Breukelen B., den Hertog J.,
RA Slijper M., Heck A.J.R.;
RT "Online automated in vivo zebrafish phosphoproteomics: from large-scale
RT analysis down to a single embryo.";
RL J. Proteome Res. 7:1555-1564(2008).
CC -!- SIMILARITY: Belongs to the MTFR1 family. {ECO:0000305}.
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DR EMBL; BC053148; AAH53148.1; -; mRNA.
DR RefSeq; NP_956178.1; NM_199884.1.
DR RefSeq; XP_005158551.1; XM_005158494.3.
DR AlphaFoldDB; Q7T3E8; -.
DR STRING; 7955.ENSDARP00000018738; -.
DR iPTMnet; Q7T3E8; -.
DR PaxDb; Q7T3E8; -.
DR PRIDE; Q7T3E8; -.
DR Ensembl; ENSDART00000007271; ENSDARP00000018738; ENSDARG00000003940.
DR Ensembl; ENSDART00000180992; ENSDARP00000151812; ENSDARG00000111141.
DR GeneID; 334296; -.
DR KEGG; dre:334296; -.
DR CTD; 56181; -.
DR ZFIN; ZDB-GENE-030131-6228; mtfr1l.
DR eggNOG; ENOG502QRAC; Eukaryota.
DR GeneTree; ENSGT00950000183215; -.
DR HOGENOM; CLU_083041_0_0_1; -.
DR InParanoid; Q7T3E8; -.
DR OMA; SATSECC; -.
DR OrthoDB; 1485791at2759; -.
DR PhylomeDB; Q7T3E8; -.
DR TreeFam; TF331404; -.
DR PRO; PR:Q7T3E8; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 17.
DR Bgee; ENSDARG00000003940; Expressed in brain and 23 other tissues.
DR ExpressionAtlas; Q7T3E8; baseline.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0009060; P:aerobic respiration; IBA:GO_Central.
DR GO; GO:0000266; P:mitochondrial fission; IBA:GO_Central.
DR InterPro; IPR007972; Mtfr1.
DR PANTHER; PTHR14215; PTHR14215; 1.
DR Pfam; PF05308; Mito_fiss_reg; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..309
FT /note="Mitochondrial fission regulator 1-like"
FT /id="PRO_0000341570"
FT REGION 189..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..213
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 253
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18307296"
SQ SEQUENCE 309 AA; 34899 MW; 17CA3FFE39F894B1 CRC64;
METEAEVIPI WQNKPHGSTR SVVRRIGSTL PLKPCPRACF QELPGLPSMR SLDGPLVPTL
ADIAWIADDE EETYARVRSD TRPLRHEWRP TPLLVMHRNS SVPNFRREGR RVEGLRKPGV
TALNRTTALQ DELSRLRAQI AKIVAADSDS NPITPDLLSP DDTSMGFSMA PFETAAYQPP
PTASFVISDV TEEDEEEEEE EDREEEEEDV SELVPDPMPP VSMTASATFD LDRPTMDFRE
PEEDTVSLSK STSFADVMDM LKDMNRLKMS KDRYNRGCTS LREEDSASLI SEALRKKFVL
KDDDISMRK