ID   MFS11_XENTR             Reviewed;         445 AA.
AC   Q6DIT7;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=UNC93-like protein MFSD11;
DE   AltName: Full=Major facilitator superfamily domain-containing protein 11;
GN   Name=mfsd11; ORFNames=TNeu052c09.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the unc-93 family. {ECO:0000305}.
CC   -!- CAUTION: Despite its name it is related to the unc-93 family and not to
CC       the major facilitator superfamily. {ECO:0000305}.
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DR   EMBL; CR942618; CAJ82804.1; -; mRNA.
DR   EMBL; BC075448; AAH75448.1; -; mRNA.
DR   RefSeq; NP_001004954.1; NM_001004954.1.
DR   RefSeq; XP_012827087.1; XM_012971633.2.
DR   RefSeq; XP_012827088.1; XM_012971634.2.
DR   RefSeq; XP_012827089.1; XM_012971635.2.
DR   AlphaFoldDB; Q6DIT7; -.
DR   SMR; Q6DIT7; -.
DR   STRING; 8364.ENSXETP00000022505; -.
DR   PaxDb; Q6DIT7; -.
DR   DNASU; 448366; -.
DR   GeneID; 448366; -.
DR   KEGG; xtr:448366; -.
DR   CTD; 79157; -.
DR   Xenbase; XB-GENE-1003745; mfsd11.
DR   eggNOG; KOG3098; Eukaryota.
DR   HOGENOM; CLU_025356_2_0_1; -.
DR   InParanoid; Q6DIT7; -.
DR   OrthoDB; 663893at2759; -.
DR   PhylomeDB; Q6DIT7; -.
DR   Proteomes; UP000008143; Chromosome 10.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000019492; Expressed in 4-cell stage embryo and 13 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR010291; Ion_channel_UNC-93.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF05978; UNC-93; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..445
FT                   /note="UNC93-like protein MFSD11"
FT                   /id="PRO_0000305024"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        385..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        40
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        163
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   445 AA;  48591 MW;  0881791065AE1062 CRC64;
     MSPESRKLLN IIILGIGFMF MFTAFQTSGN VAQTVISSLN STSFHGSGYT SLAIIYSVFS
     ASNLIAPSIV AVIGCQMSMF LSGLLYSAYI AMFIQPYTWS FYTLSVLIGI AAAVLWTAQG
     SCLTINSDDT TIGKHSGIFW ALLQFSMLFG NLFIYLAWKG EINISDSDRR TVFIALTVIS
     LVGSVLFFLI RTPESDDAQE DDISNSAADA EGTMSAQSCF AKAIDAFKRS LKLSITKEML
     LLSILVAYTG LELTFYSGVY GTCIGSMKVF EADAKSLIGL SGIFVGLGEV LGGGLFGLLG
     KYNYFGRNPV VILGVVVHFL AFYMIYLYMP SDAPIASREG TYLRAFINPS KTIALACSFL
     LGLGDSCYNT QMLSILGSLY PDNSAPAFAV FKFVQSVSAA VAFFYSNYLL LHWQLLILVI
     FGFFGTISFF FVEWGLTRRS QYNSM