ID   MFS6L_DANRE             Reviewed;         542 AA.
AC   Q6DBX0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Major facilitator superfamily domain-containing protein 6-like;
GN   Name=mfsd6l; ORFNames=zgc:101042;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. MFSD6 family.
CC       {ECO:0000305}.
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DR   EMBL; BC078328; AAH78328.1; -; mRNA.
DR   RefSeq; NP_001003586.1; NM_001003586.2.
DR   AlphaFoldDB; Q6DBX0; -.
DR   STRING; 7955.ENSDARP00000010172; -.
DR   PaxDb; Q6DBX0; -.
DR   Ensembl; ENSDART00000007119; ENSDARP00000010172; ENSDARG00000014761.
DR   GeneID; 445192; -.
DR   KEGG; dre:445192; -.
DR   CTD; 162387; -.
DR   ZFIN; ZDB-GENE-040801-105; mfsd6l.
DR   eggNOG; KOG3762; Eukaryota.
DR   GeneTree; ENSGT00530000063599; -.
DR   HOGENOM; CLU_013133_4_0_1; -.
DR   InParanoid; Q6DBX0; -.
DR   OMA; GQLDCFL; -.
DR   OrthoDB; 453672at2759; -.
DR   PhylomeDB; Q6DBX0; -.
DR   TreeFam; TF314366; -.
DR   PRO; PR:Q6DBX0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000014761; Expressed in tail and 18 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR024989; MFS_assoc_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF12832; MFS_1_like; 1.
DR   SUPFAM; SSF103473; SSF103473; 2.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..542
FT                   /note="Major facilitator superfamily domain-containing
FT                   protein 6-like"
FT                   /id="PRO_0000321946"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        352..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        381..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        404..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        444..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        469..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   542 AA;  59716 MW;  50751566F3579B8E CRC64;
     MKKGAMQKSK QWNVKGAVRL ASVFHFLHSC GSGCLLPFLT LYFRHLGLSA AMIGIIMASK
     HLLALLWRPF SSVLARQYDK RRTVIVGSLL SSALVVLPLL LFPSAGILVE SGRCNTSQPD
     ADPTLPLAVI EQMTVPVGSN ATVYSVNQTS VSTNQTLEDN TLVNHSRSAR GLRSLKKEEE
     PHSEFLGSLK VMDAQHQMFF LVLLVTALWE FVAVPLEWTA DDGLYEYLDF VDATDRHSGV
     KVWKHVGAAF GSCLVGVLVT NLFCRIGNSV EFYSYTVLMI LTVPASALLP IYLRKRERPT
     SGGFKALQLV HGNPQAILCA VTVILTGMVT SAVSDFLLWL MQDCGAMEIH MGICLALAHL
     SHTGFSPIAG PLSRFLKYHG WMLVLAVVGL AMQCLYYSFL WSPWAVMPAQ LLAGFSTGAL
     WWSVTSQSED IATPGTEKTI LRLFEAFSLD MGAALGSLIA GFVVQKFGVN VLFQGASVML
     AVWSSALAVL KWKIPRQRRI NYSRLLAADT EVSESESDQE KDWLETAMED DRRNNKWTVN
     KS