ID   MFTB_MYCTU              Reviewed;         109 AA.
AC   P95038; L0T4K6;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 2.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Peptide chaperone MftB {ECO:0000305};
GN   Name=mftB {ECO:0000303|PubMed:21223593}; OrderedLocusNames=Rv0692;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21223593; DOI=10.1186/1471-2164-12-21;
RA   Haft D.H.;
RT   "Bioinformatic evidence for a widely distributed, ribosomally produced
RT   electron carrier precursor, its maturation proteins, and its
RT   nicotinoprotein redox partners.";
RL   BMC Genomics 12:21-21(2011).
CC   -!- FUNCTION: Peptide chaperone involved in the biosynthesis of the enzyme
CC       cofactor mycofactocin (MFT). Binds MftA and MftC with high affinity,
CC       and is essential for MftC activity on MftA, likely via the formation of
CC       a ternary complex. {ECO:0000250|UniProtKB:A0PM48}.
CC   -!- SIMILARITY: Belongs to the peptide chaperone MftB family.
CC       {ECO:0000305}.
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DR   EMBL; AL123456; CCP43436.1; -; Genomic_DNA.
DR   PIR; G70640; G70640.
DR   RefSeq; NP_215206.1; NC_000962.3.
DR   RefSeq; WP_003403486.1; NC_000962.3.
DR   AlphaFoldDB; P95038; -.
DR   SMR; P95038; -.
DR   STRING; 83332.Rv0692; -.
DR   PaxDb; P95038; -.
DR   DNASU; 888285; -.
DR   GeneID; 888285; -.
DR   KEGG; mtu:Rv0692; -.
DR   TubercuList; Rv0692; -.
DR   eggNOG; COG0535; Bacteria.
DR   OMA; QGPYLHA; -.
DR   Proteomes; UP000001584; Chromosome.
DR   InterPro; IPR023850; MftB.
DR   TIGRFAMs; TIGR03967; mycofact_MftB; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..109
FT                   /note="Peptide chaperone MftB"
FT                   /id="PRO_0000415283"
SQ   SEQUENCE   109 AA;  12076 MW;  F9D1767B50641A0D CRC64;
     MWGLLTVPAP AQARRADSSE FDPDRGWRLH PQVAVRPEPF GALLYHFGTR KLSFLKNRTI
     LAVVQTLADY PDIRSACRGA GVDDCDQDPY LHALSVLAGS NMLVPRQTT