ID   MG101_ASHGO             Reviewed;         254 AA.
AC   Q75DV9;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Mitochondrial genome maintenance protein MGM101;
DE   Flags: Precursor;
GN   Name=MGM101; OrderedLocusNames=ABL086C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Performs an essential function in the repair of oxidatively
CC       damaged mtDNA that is required for the maintenance of the mitochondrial
CC       genome. Binds to DNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MGM101 family. {ECO:0000305}.
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DR   EMBL; AE016815; AAS50685.1; -; Genomic_DNA.
DR   RefSeq; NP_982861.1; NM_208214.1.
DR   AlphaFoldDB; Q75DV9; -.
DR   STRING; 33169.AAS50685; -.
DR   PRIDE; Q75DV9; -.
DR   EnsemblFungi; AAS50685; AAS50685; AGOS_ABL086C.
DR   GeneID; 4618942; -.
DR   KEGG; ago:AGOS_ABL086C; -.
DR   eggNOG; ENOG502RXU4; Eukaryota.
DR   HOGENOM; CLU_028692_1_0_1; -.
DR   InParanoid; Q75DV9; -.
DR   OMA; TKIWTRK; -.
DR   Proteomes; UP000000591; Chromosome II.
DR   GO; GO:0000262; C:mitochondrial chromosome; IEA:InterPro.
DR   GO; GO:0042645; C:mitochondrial nucleoid; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0036297; P:interstrand cross-link repair; IBA:GO_Central.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IBA:GO_Central.
DR   GO; GO:0000725; P:recombinational repair; IBA:GO_Central.
DR   InterPro; IPR009446; Mgm101.
DR   PANTHER; PTHR31404; PTHR31404; 1.
DR   Pfam; PF06420; Mgm101p; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; DNA-binding; Mitochondrion; Mitochondrion nucleoid;
KW   Reference proteome; Transit peptide.
FT   TRANSIT         1..32
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           33..254
FT                   /note="Mitochondrial genome maintenance protein MGM101"
FT                   /id="PRO_0000045814"
SQ   SEQUENCE   254 AA;  28003 MW;  B14E49F6611021F0 CRC64;
     MIRFCSARLI QRGLHTAVAK PVMATSTAAS RAAASKMAGA QAETGVVGSR LVPGYGRTLT
     RALGGQVLEA DTEGGGHVMT EGSVDWRRSF HGLGAKPFAA PVQEELARAL EPLDIEIKPD
     GLLYLPEIKY RRILNRAFGA GGWGLAPRSD TIVTAKLVTR EYALVCHGQL VSVARGEQDY
     FIDTGIPTAT EGCKSNALMR CCKDLGIGSE LWDPVFIKKF KKEYCMERFV EHLTTKKKKK
     IWLRKDREVE YPYK