ID   MG101_CANAL             Reviewed;         275 AA.
AC   Q5AI97; A0A1D8PCS5;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2017, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Mitochondrial genome maintenance protein MGM101;
DE   Flags: Precursor;
GN   Name=MGM101; OrderedLocusNames=CAALFM_C102660CA;
GN   ORFNames=CaO19.10473, CaO19.2956;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Performs an essential function in the repair of oxidatively
CC       damaged mtDNA that is required for the maintenance of the mitochondrial
CC       genome. Binds to DNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MGM101 family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW25947.1; -; Genomic_DNA.
DR   RefSeq; XP_721455.2; XM_716362.2.
DR   AlphaFoldDB; Q5AI97; -.
DR   STRING; 237561.Q5AI97; -.
DR   GeneID; 3636820; -.
DR   KEGG; cal:CAALFM_C102660CA; -.
DR   CGD; CAL0000189590; MGM101.
DR   VEuPathDB; FungiDB:C1_02660C_A; -.
DR   eggNOG; ENOG502RXU4; Eukaryota.
DR   HOGENOM; CLU_028692_1_0_1; -.
DR   InParanoid; Q5AI97; -.
DR   OMA; TKIWTRK; -.
DR   OrthoDB; 1194520at2759; -.
DR   PRO; PR:Q5AI97; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0000262; C:mitochondrial chromosome; IEA:InterPro.
DR   GO; GO:0042645; C:mitochondrial nucleoid; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0036297; P:interstrand cross-link repair; IBA:GO_Central.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IBA:GO_Central.
DR   GO; GO:0000725; P:recombinational repair; IBA:GO_Central.
DR   InterPro; IPR009446; Mgm101.
DR   PANTHER; PTHR31404; PTHR31404; 1.
DR   Pfam; PF06420; Mgm101p; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; DNA-binding; Mitochondrion; Mitochondrion nucleoid;
KW   Reference proteome; Transit peptide.
FT   TRANSIT         1..18
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..275
FT                   /note="Mitochondrial genome maintenance protein MGM101"
FT                   /id="PRO_0000045815"
FT   REGION          34..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   275 AA;  30744 MW;  F73CE5A90386E0C6 CRC64;
     MFNLIRLGFP RTSIIRYYSS TAVNQAKVYS RTYKRAGPVT KSSTSTSRST STDASPASSS
     PPKESVSDIE PSSEVPVKST TSYILHDAPL EASNKNNGET INWSDSFHGL GAQPFSKEIA
     EILLAPVAEE DIEIKPDGLL YLPEIKYRRV LNRAFGPGGW GLAPRTESLV TSGQISREYG
     LICHGRLVSI ARGEQDYFGG EEKLTTALEG CKSNALMRCC KDLGIASELW DPSFIRRWKK
     KYCEEIFVEH VNTKKKKKIW KLKSIKTIDY PYKMT