ID   MG101_DICDI             Reviewed;         377 AA.
AC   Q8MYF0; Q54ZJ1;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Mitochondrial genome maintenance protein mgm101 homolog;
DE   Flags: Precursor;
GN   Name=mgm101; ORFNames=DDB_G0277451;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Performs an essential function in the repair of oxidatively
CC       damaged mtDNA that is required for the maintenance of the mitochondrial
CC       genome. Binds to DNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MGM101 family. {ECO:0000305}.
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DR   EMBL; AAFI02000020; EAL68688.1; -; Genomic_DNA.
DR   RefSeq; XP_642651.1; XM_637559.1.
DR   AlphaFoldDB; Q8MYF0; -.
DR   BioGRID; 1246070; 1.
DR   STRING; 44689.DDB0304673; -.
DR   PaxDb; Q8MYF0; -.
DR   EnsemblProtists; EAL68688; EAL68688; DDB_G0277451.
DR   GeneID; 8621067; -.
DR   KEGG; ddi:DDB_G0277451; -.
DR   dictyBase; DDB_G0277451; mgm101.
DR   eggNOG; ENOG502RXU4; Eukaryota.
DR   HOGENOM; CLU_734520_0_0_1; -.
DR   InParanoid; Q8MYF0; -.
DR   OMA; RPYALYC; -.
DR   PRO; PR:Q8MYF0; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0000262; C:mitochondrial chromosome; IEA:InterPro.
DR   GO; GO:0042645; C:mitochondrial nucleoid; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; ISS:dictyBase.
DR   GO; GO:0003677; F:DNA binding; ISS:dictyBase.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0036297; P:interstrand cross-link repair; IBA:GO_Central.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; ISS:dictyBase.
DR   GO; GO:0000725; P:recombinational repair; IBA:GO_Central.
DR   InterPro; IPR009446; Mgm101.
DR   PANTHER; PTHR31404; PTHR31404; 1.
DR   Pfam; PF06420; Mgm101p; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; DNA-binding; Mitochondrion; Mitochondrion nucleoid;
KW   Reference proteome; Transit peptide.
FT   TRANSIT         1..12
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           13..377
FT                   /note="Mitochondrial genome maintenance protein mgm101
FT                   homolog"
FT                   /id="PRO_0000367252"
FT   REGION          254..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..309
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   377 AA;  42622 MW;  0CEC4BF752C03EB5 CRC64;
     MKRFISTTSL RVLSNLNKNN NNNNKFNKSI VGVFNREFSS SNEGLNKVNF GENNNSSTTE
     PTKVLFNDSQ FYQEDKYQGI SKEPFSKEIV DTLLADLNPD DIEIKPDGLI YLPEIKYRRI
     LNQAFGPGGW ALKPFGPPVV EGKTLIRPYA LYCLGRYVAE SIGEQQYVPN SFISFATATE
     SAKSNALVRC CKDLGIGSSL WDPIFIRQWK SEYATERWCE NSKTKERRLF WFLSNRSENQ
     LPYPWKESDF NQVPSNSSYS SSSSSINNNS NSSNNNNNNS DSSSSINQPQ QETISYHQDD
     SSSPSSKITE QQDDSEDIDI DDVVPPQLKK YAGKTWRQLV ADPKGLSYLQ WASSSFDNAP
     KIKSQATAIL EFINKSQ