ID   MG101_YARLI             Reviewed;         289 AA.
AC   Q6C6V8;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Mitochondrial genome maintenance protein MGM101;
DE   Flags: Precursor;
GN   Name=MGM101; OrderedLocusNames=YALI0E05863g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Performs an essential function in the repair of oxidatively
CC       damaged mtDNA that is required for the maintenance of the mitochondrial
CC       genome. Binds to DNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MGM101 family. {ECO:0000305}.
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DR   EMBL; CR382131; CAG79185.1; -; Genomic_DNA.
DR   RefSeq; XP_503604.1; XM_503604.1.
DR   AlphaFoldDB; Q6C6V8; -.
DR   STRING; 4952.CAG79185; -.
DR   EnsemblFungi; CAG79185; CAG79185; YALI0_E05863g.
DR   GeneID; 2912335; -.
DR   KEGG; yli:YALI0E05863g; -.
DR   VEuPathDB; FungiDB:YALI0_E05863g; -.
DR   HOGENOM; CLU_028692_0_3_1; -.
DR   InParanoid; Q6C6V8; -.
DR   OMA; ASELWEP; -.
DR   Proteomes; UP000001300; Chromosome E.
DR   GO; GO:0000262; C:mitochondrial chromosome; IEA:InterPro.
DR   GO; GO:0042645; C:mitochondrial nucleoid; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0036297; P:interstrand cross-link repair; IBA:GO_Central.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IBA:GO_Central.
DR   GO; GO:0000725; P:recombinational repair; IBA:GO_Central.
DR   InterPro; IPR009446; Mgm101.
DR   PANTHER; PTHR31404; PTHR31404; 1.
DR   Pfam; PF06420; Mgm101p; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; DNA-binding; Mitochondrion; Mitochondrion nucleoid;
KW   Reference proteome; Transit peptide.
FT   TRANSIT         1..20
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..289
FT                   /note="Mitochondrial genome maintenance protein MGM101"
FT                   /id="PRO_0000045820"
FT   REGION          24..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   289 AA;  31361 MW;  7A004176EED7C59E CRC64;
     MRPTVALVVA RGVRAMGYRT AAAATKPAAA SATSAPATPA KKPAASSYWR KAASAASTAS
     VSNATKKTPV AASSPAAEPI EADDMPQVDT STVDQAPTFQ YPEGAQSNVF QHMNQREIDW
     EQSFQGLGSQ AFSKEAAQVL QAPLTVEDIE ITPDGLLYLP EIKYRRVLNA AFGPGGWGLA
     PRSDTVVTDK IVTREYGLIC EGRLVSVARG EQTYFNEDGV PTASEGCKSN AMMRCCKDLG
     VASELWEPKF IRKFKAQHCE EVWGTHVVNK RKKKLWKLKG ETLAYPYQE