MGLC_HAEIN
ID MGLC_HAEIN Reviewed; 336 AA.
AC P44885;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Galactoside transport system permease protein MglC;
GN Name=mglC; OrderedLocusNames=HI_0824;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC galactoside. Probably responsible for the translocation of the
CC substrate across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR EMBL; L42023; AAC22483.1; -; Genomic_DNA.
DR PIR; I64096; I64096.
DR RefSeq; NP_438984.1; NC_000907.1.
DR RefSeq; WP_005652434.1; NC_000907.1.
DR AlphaFoldDB; P44885; -.
DR STRING; 71421.HI_0824; -.
DR PRIDE; P44885; -.
DR EnsemblBacteria; AAC22483; AAC22483; HI_0824.
DR KEGG; hin:HI_0824; -.
DR PATRIC; fig|71421.8.peg.865; -.
DR eggNOG; COG4211; Bacteria.
DR HOGENOM; CLU_028880_1_0_6; -.
DR OMA; DWFKAFL; -.
DR PhylomeDB; P44885; -.
DR BioCyc; HINF71421:G1GJ1-865-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR001851; ABC_transp_permease.
DR InterPro; IPR030158; MglC.
DR PANTHER; PTHR32196:SF18; PTHR32196:SF18; 1.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..336
FT /note="Galactoside transport system permease protein MglC"
FT /id="PRO_0000060108"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 336 AA; 35727 MW; F8B1474A9026B36B CRC64;
MSALEKNKSF DLLKQNAIYF VLLILLGIII AQDPTFLNLV NFSNILTQSS VRLIIALGVA
GLLITQGTDL SAGRQVGLAA VISATMLQSM ENINRVFPEM GQIPIPVVIL AVCAIGAVIG
LVNGLVIAYL NVTPFIATMG TMIIIYGFNS LYYDAVGGSP IAGFSENFST FAQGFFRVGS
FKLSYITIYA AIAALLVWIM WNKTRFGKNV FAIGGNPEAA KVSGVNVARN LVAIYMIAGM
FYAFGGMLEA GRIGSATNNL GFMYELDAIA ACVVGGVSFA GGVGTVIGVI TGVIIFTVIN
YGLTYIGVNP YWQYIIKGSI IILAVAIDSL KYAKKK