MGLC_SALTY
ID MGLC_SALTY Reviewed; 336 AA.
AC Q56036;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2002, sequence version 2.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Galactoside transport system permease protein MglC;
GN Name=mglC; OrderedLocusNames=STM2188;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=8675022; DOI=10.1016/0378-1119(96)00072-8;
RA Stamm L.V., Young N.R., Frye J.G.;
RT "Sequences of the Salmonella typhimurium mglA and mglC genes.";
RL Gene 171:131-132(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC galactoside. Probably responsible for the translocation of the
CC substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC44150.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U40492; AAC44150.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AE006468; AAL21092.1; -; Genomic_DNA.
DR RefSeq; NP_461133.1; NC_003197.2.
DR RefSeq; WP_001275101.1; NC_003197.2.
DR AlphaFoldDB; Q56036; -.
DR STRING; 99287.STM2188; -.
DR PaxDb; Q56036; -.
DR EnsemblBacteria; AAL21092; AAL21092; STM2188.
DR GeneID; 1253710; -.
DR KEGG; stm:STM2188; -.
DR PATRIC; fig|99287.12.peg.2315; -.
DR HOGENOM; CLU_028880_1_0_6; -.
DR OMA; DWFKAFL; -.
DR PhylomeDB; Q56036; -.
DR BioCyc; SENT99287:STM2188-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR001851; ABC_transp_permease.
DR InterPro; IPR030158; MglC.
DR PANTHER; PTHR32196:SF18; PTHR32196:SF18; 1.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..336
FT /note="Galactoside transport system permease protein MglC"
FT /id="PRO_0000060107"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 38..52
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 74..106
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 128..180
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 202..226
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 248..256
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 278
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 300..305
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 327..336
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 336 AA; 35607 MW; 0CDDCC0A4C5B86FC CRC64;
MSALNKKSFL TWLKEGGIYV VLLVLLAIII FQDPTFLSLL NLSNILTQSS VRIIIALGVA
GLIVTQGTDL SAGRQVGLAA VVAATLLQSM ENANKVFPEM ATMPIALVIL IVCAIGAVIG
LVNGIIIAYL NVTPFITTLG TMIIVYGINS LYYDFVGASP ISGFDSGFST FAQGFVAMGS
FRLSYITFYA LIAVAFVWVL WNKTRFGKNI FAIGGNPEAA KVSGVNVALN LLMIYALSGV
FYAFGGLLEA GRIGSATNNL GFMYELDAIA ACVVGGVSFS GGVGTVFGVV TGVIIFTVIN
YGLTYIGVNP YWQYIIKGGI IIFAVALDSL KYARKK
