ID   MGP3_MYCPN              Reviewed;        1218 AA.
AC   Q50341;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Mgp-operon protein 3;
DE            Short=Mgp3;
DE   AltName: Full=ORF-3 protein;
DE   Flags: Precursor;
GN   OrderedLocusNames=MPN_142; ORFNames=MP012;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=2468577; DOI=10.1016/0378-1119(88)90323-x;
RA   Inamine J.M., Loechel S., Hu P.C.;
RT   "Analysis of the nucleotide sequence of the P1 operon of Mycoplasma
RT   pneumoniae.";
RL   Gene 73:175-183(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=11271496;
RX   DOI=10.1002/1522-2683(200011)21:17<3765::aid-elps3765>3.0.co;2-6;
RA   Regula J.T., Ueberle B., Boguth G., Goerg A., Schnoelzer M., Herrmann R.,
RA   Frank R.;
RT   "Towards a two-dimensional proteome map of Mycoplasma pneumoniae.";
RL   Electrophoresis 21:3765-3780(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M21519; AAA88326.1; -; Genomic_DNA.
DR   EMBL; U00089; AAB95660.1; -; Genomic_DNA.
DR   PIR; JS0069; JS0069.
DR   RefSeq; NP_109830.1; NC_000912.1.
DR   RefSeq; WP_010874499.1; NC_000912.1.
DR   AlphaFoldDB; Q50341; -.
DR   SMR; Q50341; -.
DR   IntAct; Q50341; 2.
DR   EnsemblBacteria; AAB95660; AAB95660; MPN_142.
DR   KEGG; mpn:MPN_142; -.
DR   PATRIC; fig|272634.6.peg.156; -.
DR   HOGENOM; CLU_268940_0_0_14; -.
DR   OMA; KLNESWP; -.
DR   BioCyc; MPNE272634:G1GJ3-240-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   InterPro; IPR045839; MGP3_C.
DR   InterPro; IPR007885; MgpC.
DR   Pfam; PF19342; MGP3_C; 1.
DR   Pfam; PF05220; MgpC; 1.
PE   1: Evidence at protein level;
KW   Cell adhesion; Cell membrane; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..1218
FT                   /note="Mgp-operon protein 3"
FT                   /id="PRO_0000021721"
FT   TRANSMEM        1121..1141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          109..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          213..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          262..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          411..440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1192..1218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..234
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        266..282
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..348
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1201..1218
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1218 AA;  130457 MW;  4DA29BCE41538311 CRC64;
     MKSKLKLKRY LLFLPLLPLG TLSLANTYLL QDHNTLTPYT PFTTPLNGGL DVVRAAHLHP
     SYELVDWKRV GDTKLVALVR SALVRVKFQD TTSSDQSNTN QNALSFDTQE SQKALNGSQS
     GSSDTSGSNS QDFASYVLIF KAAPRATWVF ERKIKLALPY VKQESQGSGD QGSNGKGSLY
     KTLQDLLVEQ PVTPYTPNAG LARVNGVAQD TVHFGSGQES SWNSQRSQKG LKNNPGPKAV
     TGFKLDKGRA YRKLNESWPV YEPLDSTKEG KGKDESSWKN SEKTTAENDA PLVGMVGSGA
     AGSASSLQGN GSNSSGLKSL LRSAPVSVPP SSTSNQTLSL SNPAPVGPQA VVSQPAGGAT
     AAVSVNRTAS DTATFSKYLN TAQALHQMGV IVPGLEKWGG NNGTGVVASR QDATSTNLPH
     AAGASQTGLG TGSPREPALT ATSQRAVTVV AGPLRAGNSS ETDALPNVIT QLYHTSTAQL
     AYLNGQIVVM GSDRVPSLWY WVVGEDQESG KATWWAKTEL NWGTDKQKQF VENQLGFKDD
     SNSDSKNSNL KAQGLTQPAY LIAGLDVVAD HLVFAAFKAG AVGYDMTTDS SASTYNQALA
     WSTTAGLDSD GGYKALVENT AGLNGPINGL FTLLDTFAYV TPVSGMKGGS QNNEEVQTTY
     PVKSDQKATA KIASLINASP LNSYGDDGVT VFDALGLNFN FKLNEERLPS RTDQLLVYGI
     VNESELKSAR ENAQSTSDDN SNTKVKWTNT ASHYLPVPYY YSANFPEAGN RRRAEQRNGV
     KISTLESQAT DGFANSLLNF GTGLKAGVDP APVARGHKPN YSAVLLVRGG VVRLNFNPDT
     DKLLDSTDKN SEPISFSYTP FGSAESAVDL TTLKDVTYIA ESGLWFYTFD NGEKPTYDGK
     QQQVKNRKGY AVITVSRTGI EFNEDANTTT LSQAPAALAV QNGIASSQDD LTGILPLSDE
     FSAVITKDQT WTGKVDIYKN TNGLFEKDDQ LSENVKRRDN GLVPIYNEGI VDIWGRVDFA
     ANSVLQARNL TDKTVDEVIN NPDILQSFFK FTPAFDNQRA MLVGEKTSDT TLTVKPKIEY
     LDGNFYGEDS KIAGIPLNID FPSRIFAGFA ALPSWVIPVS VGSSVGILLI LLILGLGIGI
     PMYKVRKLQD SSFVDVFKKV DTLTTAVGSV YKKIITQTSV IKKAPSALKA ANNAAPKAPV
     KPAAPTAPRP PVQPPKKA