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MHR1_ASHGO
ID   MHR1_ASHGO              Reviewed;         213 AA.
AC   Q75EZ5;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Mitochondrial homologous recombination protein 1;
GN   Name=MHR1; OrderedLocusNames=AAL067W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Transcription factor involved in regulation of RNA polymerase
CC       II-dependent transcription. Also involved in regulation of
CC       mitochondrial DNA recombination, maintenance and repair, and generation
CC       of homoplasmic cells (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Mitochondrion
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL67 family. {ECO:0000305}.
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DR   EMBL; AE016814; AAS50299.1; -; Genomic_DNA.
DR   RefSeq; NP_982475.1; NM_207828.1.
DR   AlphaFoldDB; Q75EZ5; -.
DR   SMR; Q75EZ5; -.
DR   STRING; 33169.AAS50299; -.
DR   EnsemblFungi; AAS50299; AAS50299; AGOS_AAL067W.
DR   GeneID; 4618675; -.
DR   KEGG; ago:AGOS_AAL067W; -.
DR   eggNOG; ENOG502QSKX; Eukaryota.
DR   HOGENOM; CLU_092898_0_0_1; -.
DR   InParanoid; Q75EZ5; -.
DR   OMA; WENRKPS; -.
DR   Proteomes; UP000000591; Chromosome I.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; IEA:EnsemblFungi.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:EnsemblFungi.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblFungi.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:EnsemblFungi.
DR   GO; GO:0090297; P:positive regulation of mitochondrial DNA replication; IEA:EnsemblFungi.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:EnsemblFungi.
DR   InterPro; IPR024629; Mhr1.
DR   PANTHER; PTHR28184; PTHR28184; 1.
DR   Pfam; PF12829; Mhr1; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Nucleus; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; Transcription; Transcription regulation.
FT   CHAIN           1..213
FT                   /note="Mitochondrial homologous recombination protein 1"
FT                   /id="PRO_0000255961"
SQ   SEQUENCE   213 AA;  24716 MW;  C25663D9AB6C4119 CRC64;
     MSKTVGASRF RPAGWLQRAG YAPQVFVFRN LESGQVIYSQ LPTFTERQIN KNFYRPNWEN
     RKPSTRPDIW KCMAVVDLAS HEESVRLYQN LCRLRYLREV PQRKAAEQLR KRNEFGHIWY
     SAQYRPTYTQ EAVADLRECL LRARGGATVH WEDPWRMGDR AKHWAALPAV QHQFLPRMAN
     VAREESAILK QLGERAKRAF AAPAPPAPAP QSL
 
 
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