MHR1_ASHGO
ID MHR1_ASHGO Reviewed; 213 AA.
AC Q75EZ5;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Mitochondrial homologous recombination protein 1;
GN Name=MHR1; OrderedLocusNames=AAL067W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Transcription factor involved in regulation of RNA polymerase
CC II-dependent transcription. Also involved in regulation of
CC mitochondrial DNA recombination, maintenance and repair, and generation
CC of homoplasmic cells (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Mitochondrion
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL67 family. {ECO:0000305}.
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DR EMBL; AE016814; AAS50299.1; -; Genomic_DNA.
DR RefSeq; NP_982475.1; NM_207828.1.
DR AlphaFoldDB; Q75EZ5; -.
DR SMR; Q75EZ5; -.
DR STRING; 33169.AAS50299; -.
DR EnsemblFungi; AAS50299; AAS50299; AGOS_AAL067W.
DR GeneID; 4618675; -.
DR KEGG; ago:AGOS_AAL067W; -.
DR eggNOG; ENOG502QSKX; Eukaryota.
DR HOGENOM; CLU_092898_0_0_1; -.
DR InParanoid; Q75EZ5; -.
DR OMA; WENRKPS; -.
DR Proteomes; UP000000591; Chromosome I.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; IEA:EnsemblFungi.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:EnsemblFungi.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:EnsemblFungi.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblFungi.
DR GO; GO:0000002; P:mitochondrial genome maintenance; IEA:EnsemblFungi.
DR GO; GO:0090297; P:positive regulation of mitochondrial DNA replication; IEA:EnsemblFungi.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:EnsemblFungi.
DR InterPro; IPR024629; Mhr1.
DR PANTHER; PTHR28184; PTHR28184; 1.
DR Pfam; PF12829; Mhr1; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Transcription; Transcription regulation.
FT CHAIN 1..213
FT /note="Mitochondrial homologous recombination protein 1"
FT /id="PRO_0000255961"
SQ SEQUENCE 213 AA; 24716 MW; C25663D9AB6C4119 CRC64;
MSKTVGASRF RPAGWLQRAG YAPQVFVFRN LESGQVIYSQ LPTFTERQIN KNFYRPNWEN
RKPSTRPDIW KCMAVVDLAS HEESVRLYQN LCRLRYLREV PQRKAAEQLR KRNEFGHIWY
SAQYRPTYTQ EAVADLRECL LRARGGATVH WEDPWRMGDR AKHWAALPAV QHQFLPRMAN
VAREESAILK QLGERAKRAF AAPAPPAPAP QSL
