MHR1_CANAL
ID MHR1_CANAL Reviewed; 239 AA.
AC Q5A2A2; A0A1D8PDJ4;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Mitochondrial homologous recombination protein 1;
GN Name=MHR1; OrderedLocusNames=CAALFM_C105270CA;
GN ORFNames=CaO19.439, CaO19.8069;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Transcription factor involved in regulation of RNA polymerase
CC II-dependent transcription. Also involved in regulation of
CC mitochondrial DNA recombination, maintenance and repair, and generation
CC of homoplasmic cells (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Mitochondrion
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL67 family. {ECO:0000305}.
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DR EMBL; CP017623; AOW26197.1; -; Genomic_DNA.
DR RefSeq; XP_715874.1; XM_710781.2.
DR AlphaFoldDB; Q5A2A2; -.
DR SMR; Q5A2A2; -.
DR STRING; 237561.Q5A2A2; -.
DR GeneID; 3642476; -.
DR KEGG; cal:CAALFM_C105270CA; -.
DR CGD; CAL0000174972; orf19.8069.
DR VEuPathDB; FungiDB:C1_05270C_A; -.
DR eggNOG; ENOG502QSKX; Eukaryota.
DR HOGENOM; CLU_092898_1_0_1; -.
DR InParanoid; Q5A2A2; -.
DR OMA; WENRKPS; -.
DR OrthoDB; 1401988at2759; -.
DR PRO; PR:Q5A2A2; -.
DR Proteomes; UP000000559; Chromosome 1.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0000002; P:mitochondrial genome maintenance; IEA:InterPro.
DR InterPro; IPR024629; Mhr1.
DR PANTHER; PTHR28184; PTHR28184; 1.
DR Pfam; PF12829; Mhr1; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Transcription; Transcription regulation.
FT CHAIN 1..239
FT /note="Mitochondrial homologous recombination protein 1"
FT /id="PRO_0000255962"
SQ SEQUENCE 239 AA; 28356 MW; FF0B96ED123FEA98 CRC64;
MAMRTRAEKR MRKFLIEQLK TRQQNGARIA QGKKSEHELI KNNLGPQVFV FRNLFSGQVL
YSQVPAYHEN QINQQFLSPN WQNRKPSRRQ DLWKIMCVVN FNNYEYAIAA YKGLVDLRKT
RDVVQKKEAN EMRKKNDDGN IWYSGQFRPT YTQEAVADLT HVIDEFELEG TKIFWANEWH
RGDDKHWRAD LVEHDKLPVY DPRHQTVLLD IMREKAIEAF RENNTSEETI ENATEPETA