MHZ4_ORYSJ
ID MHZ4_ORYSJ Reviewed; 228 AA.
AC Q5ZEG0; Q0JR03;
DT 13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Protein MAO HUZI 4, chloroplastic {ECO:0000303|PubMed:25330236};
DE Flags: Precursor;
GN Name=MHZ4 {ECO:0000303|PubMed:25330236};
GN OrderedLocusNames=Os01g0128300 {ECO:0000312|EMBL:BAF03825.2},
GN LOC_Os01g03750 {ECO:0000305};
GN ORFNames=P0408F06.3 {ECO:0000312|EMBL:BAD52477.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION BY ETHYLENE,
RP AND DISRUPTION PHENOTYPE.
RX PubMed=25330236; DOI=10.1371/journal.pgen.1004701;
RA Ma B., Yin C.C., He S.J., Lu X., Zhang W.K., Lu T.G., Chen S.Y.,
RA Zhang J.S.;
RT "Ethylene-induced inhibition of root growth requires abscisic acid function
RT in rice (Oryza sativa L.) seedlings.";
RL PLoS Genet. 10:E1004701-E1004701(2014).
CC -!- FUNCTION: Required for neoxanthin biosynthesis, an intermediary step in
CC abscisic acid (ABA) biosynthesis. Involved in an ABA pathway that acts
CC at or downstream of ethylene receptors and positively regulates root
CC ethylene response. In coleoptiles the MHZ4-dependent ABA pathway acts
CC at or upstream of EIN2 to negatively regulate coleoptile ethylene
CC response. {ECO:0000269|PubMed:25330236}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast envelope
CC {ECO:0000305|PubMed:25330236}. Plastid, chloroplast membrane
CC {ECO:0000305|PubMed:25330236}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: In etiolated seedlings, expressed in roots,
CC coleoptiles and vascular tissues of roots. In root apexes, expressed in
CC quiescent center (QC) and root caps. In field-grown plants, expressed
CC in leaf blades, young stem nodes and the base of axillary buds and
CC adventitious roots derived from the nodes. In reproductive organs,
CC expressed in anthers and pistil of young flowers, lemma of mature
CC flowers and parts of developing grains. {ECO:0000269|PubMed:25330236}.
CC -!- INDUCTION: Induced by ethylene in roots. {ECO:0000269|PubMed:25330236}.
CC -!- DISRUPTION PHENOTYPE: Mutant etiolated seedlings display reduced
CC ethylene-response in roots and enhanced ethylene-response in
CC coleoptiles. Mature mutant plants have increased shoot length, branches
CC and adventitious roots at high node position on the shoot and impaired
CC grain filling. {ECO:0000269|PubMed:25330236}.
CC -!- MISCELLANEOUS: 'Mao huzi' means cat whiskers in Chinese.
CC {ECO:0000303|PubMed:25330236}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF03825.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP002538; BAD52477.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF03825.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014957; BAS70195.1; -; Genomic_DNA.
DR RefSeq; XP_015614499.1; XM_015759013.1.
DR AlphaFoldDB; Q5ZEG0; -.
DR STRING; 4530.OS01T0128300-00; -.
DR PaxDb; Q5ZEG0; -.
DR PRIDE; Q5ZEG0; -.
DR EnsemblPlants; Os01t0128300-00; Os01t0128300-00; Os01g0128300.
DR GeneID; 4325995; -.
DR Gramene; Os01t0128300-00; Os01t0128300-00; Os01g0128300.
DR KEGG; osa:4325995; -.
DR eggNOG; ENOG502QVVZ; Eukaryota.
DR HOGENOM; CLU_057951_0_0_1; -.
DR InParanoid; Q5ZEG0; -.
DR OMA; HHGIQAS; -.
DR OrthoDB; 1588997at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0009941; C:chloroplast envelope; IDA:UniProtKB.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009688; P:abscisic acid biosynthetic process; IMP:UniProtKB.
DR GO; GO:0016123; P:xanthophyll biosynthetic process; IMP:UniProtKB.
DR InterPro; IPR025461; ABA4-like.
DR Pfam; PF14108; DUF4281; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix.
FT TRANSIT 1..41
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 42..228
FT /note="Protein MAO HUZI 4, chloroplastic"
FT /id="PRO_5006487635"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 195..215
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 228 AA; 24422 MW; 44A03E17017F6015 CRC64;
MAALLLLSSA ARVGVAAPLA LRQQRPVVLP GGQLRTGSGA GAASAWAARP LRPELAAVSR
PAVPARGRAP LFRPRAWMAS SQIASSAFTW GTIAVLPFYT LMVVAPNADV TKRAVDSSAP
YVALGILYAY LLYLSWTPDT LRAMFASKYW LPELTGIVRM FASEMTVASA WIHLLAVDLF
AARQVYHDGI KNNIETRHSV SLCLLFCPIG IATHVLTKVL AGSIGRSH
